{"schema_version":"1","generated_at":"2026-11-05T03:51:43.220Z","data_as_of":"2026-11-04","url":"https://www.findmykol.com/kol/brian-agan","json_url":"https://www.findmykol.com/kol/brian-agan/profile.json","record_kind":"full","profile_kind":"clinical","person":{"slug":"brian-agan","name":"Brian Agan","credential":"MD","title":"Deputy Science Director, Infectious Disease Clinical Research Program (IDCRP)","specialty":"Infectious Disease","specialty_raw":"Infectious Disease","therapeutic_area":"Infectious Disease","therapeutic_areas":["Infectious Disease"],"institution":"Henry M. Jackson Foundation","institution_url":"https://www.findmykol.com/institution/henry-m-jackson-foundation","city":"Bethesda","state":"MD","region":{"label":"Northeast","url":"https://www.findmykol.com/region/northeast"},"country":{"name":"United States","code":"US","status":"verified"}},"identifiers":{"npi":"1669434718","orcid":"0000-0002-5114-1669","openalex":"A5000848132"},"summary":"Brian Agan is Deputy Science Director, Infectious Disease Clinical Research Program (IDCRP) at Henry M. Jackson Foundation. OpenAlex indexes 325 publications with 8,618 citations (h-index 45); ClinicalTrials.gov lists 2 registered studies with this person as an investigator.","overview":{"text":"Brian Agan, M.D., is Deputy Science Director, Infectious Disease Clinical Research Program (IDCRP) at Henry M. Jackson Foundation. The public record shows 325 publications with 8,618 citations (h-index 45), centered on HIV/AIDS Research and Interventions, HIV Research and Treatment, HIV-related health complications and treatments. It also documents an investigator role on 2 registered clinical trials, 1 NIH-funded awards (2024–2025).","bullets":["Most recent indexed publication: 2026 · The Journal of infectious diseases","Top research focus: HIV/AIDS Research and Interventions","2 registered trials on ClinicalTrials.gov"],"generated_at":"2026-11-04"},"focus":{"indications":[{"label":"HIV","therapeutic_area":"Infectious Disease","trials":2,"topics":0,"strength":7},{"label":"HIV Infections","therapeutic_area":"Infectious Disease","trials":2,"topics":0,"strength":6},{"label":"Pneumonia","therapeutic_area":"Infectious Disease","trials":1,"topics":0,"strength":3},{"label":"Hypertension","therapeutic_area":"Cardiology","trials":0,"topics":0,"strength":1},{"label":"Gastroesophageal Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Lymphoma","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"COVID-19","therapeutic_area":"Infectious Disease","trials":0,"topics":0,"strength":1},{"label":"Lupus (SLE)","therapeutic_area":"Rheumatology/Immunology","trials":0,"topics":0,"strength":1},{"label":"MDS / MPN","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Parkinson's Disease","therapeutic_area":"Neurology","trials":0,"topics":0,"strength":1},{"label":"Head & Neck Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Tuberculosis","therapeutic_area":"Infectious Disease","trials":0,"topics":0,"strength":1},{"label":"COPD","therapeutic_area":"Respiratory","trials":0,"topics":0,"strength":1},{"label":"Type 2 Diabetes","therapeutic_area":"Endocrinology/Metabolic","trials":0,"topics":0,"strength":1},{"label":"Dyslipidemia / Lipid Disorders","therapeutic_area":"Cardiology","trials":0,"topics":0,"strength":1},{"label":"Leukemia (AML/ALL/CML/CLL)","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Obesity","therapeutic_area":"Endocrinology/Metabolic","trials":0,"topics":0,"strength":1},{"label":"Viral Hepatitis (B/C)","therapeutic_area":"Gastroenterology","trials":0,"topics":0,"strength":1},{"label":"Alzheimer's / Dementia","therapeutic_area":"Neurology","trials":0,"topics":0,"strength":1},{"label":"Sepsis / Serious Bacterial","therapeutic_area":"Infectious Disease","trials":0,"topics":0,"strength":1},{"label":"Chronic Kidney Disease","therapeutic_area":"Nephrology","trials":0,"topics":0,"strength":1},{"label":"Substance Use Disorders","therapeutic_area":"Psychiatry","trials":0,"topics":0,"strength":1},{"label":"Epilepsy","therapeutic_area":"Neurology","trials":0,"topics":0,"strength":1},{"label":"Idiopathic Pulmonary Fibrosis","therapeutic_area":"Respiratory","trials":0,"topics":0,"strength":1}],"research_topics":["HIV/AIDS Research and Interventions","HIV Research and Treatment","HIV-related health complications and treatments","HIV/AIDS drug development and treatment","SARS-CoV-2 and COVID-19 Research"],"works_with":{"total":1,"shown":1,"withheld":0,"rows":[{"name":"Henry M. 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Analyzing Robustness and Frailty: Musculoskeletal Injuries, Fractures, and Hospitalizations in U.S. Military Members with and without HIV","society":"IDSA","meeting":"IDWeek","year":2025,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1093/ofid/ofaf695.456","source_url":"https://doi.org/10.1093/ofid/ofaf695.456","status":"verified"},{"title":"P-235. Fracture and Musculoskeletal Injury Risk in Active Duty Military with HIV Compared to Those without HIV: A Retrospective Virtual Cohort Study","society":"IDSA","meeting":"IDWeek","year":2025,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1093/ofid/ofaf695.457","source_url":"https://doi.org/10.1093/ofid/ofaf695.457","status":"verified"},{"title":"P-252. A New Model of HIV Disease Progression Based on the Accumulation of Non-AIDS Comorbidities","society":"IDSA","meeting":"IDWeek","year":2025,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1093/ofid/ofaf695.473","source_url":"https://doi.org/10.1093/ofid/ofaf695.473","status":"verified"}],"source":"congress"},"publications":{"total":29,"shown":5,"withheld":24,"matched_by":"ORCID record, linked to PubMed","recent":[{"title":"Is Cellular Senescence a Biological Feature of Long COVID? A Transcriptomic Analysis Across Comparative Postacute Sequelae Phenotypes.","year":2026,"journal":"The Journal of infectious diseases","types":["Journal Article"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/42340243/","status":"verified"},{"title":"Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.","year":2026,"journal":"medRxiv : the preprint server for health sciences","types":["Journal Article","Preprint"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/42326826/","status":"verified"},{"title":"NLRP3 Activation and Impaired TGF-β Anti-Inflammatory Pathways Predict Vascular Risk in PWH on ART.","year":2026,"journal":"medRxiv : the preprint server for health sciences","types":["Journal Article","Preprint"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/42845527/","status":"verified"},{"title":"RNAemia and Severe COVID-19: Candidate Treatment Targets Identified Through Transcriptomics.","year":2026,"journal":"The Journal of infectious diseases","types":["Journal Article"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/42525560/","status":"verified"},{"title":"Statistical Accuracy of Administratively Recorded Race/Ethnicity in the Military Health System and Race/Ethnicity Ascertained via Questionnaire.","year":2026,"journal":"Journal of racial and ethnic health disparities","types":["Journal Article","Research Support, N.I.H., Extramural"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/40117047/","status":"verified"}],"most_cited":{"total":325,"shown":5,"withheld":320,"rows":[{"title":"The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility","year":2005,"cited_by_count":1129,"type":"article","source_url":"https://doi.org/10.1126/science.1101160"},{"title":"Comparisons of Causes of Death and Mortality Rates Among HIV-Infected Persons","year":2006,"cited_by_count":456,"type":"article","source_url":"https://doi.org/10.1097/01.qai.0000179459.31562.16"},{"title":"Clinical Outcomes of Elite Controllers, Viremic Controllers, and Long‐Term Nonprogressors in the US Department of Defense HIV Natural History Study","year":2009,"cited_by_count":311,"type":"article","source_url":"https://doi.org/10.1086/646609"},{"title":"Trends in the incidence of cancers among HIV-infected persons and the impact of antiretroviral therapy: a 20-year cohort study","year":2008,"cited_by_count":278,"type":"article","source_url":"https://doi.org/10.1097/qad.0b013e328317cc2d"},{"title":"Increasing Rates of Obesity among HIV-Infected Persons during the HIV Epidemic","year":2010,"cited_by_count":247,"type":"article","source_url":"https://doi.org/10.1371/journal.pone.0010106"}]},"source":"publications"},"network":{"coauthors_total":40,"shown":3,"withheld":37,"coauthors":[{"name":"Anuradha Ganesan","coauthored_works":139,"profile_url":"https://www.findmykol.com/kol/anuradha-ganesan"},{"name":"Jason F. Okulicz","coauthored_works":98},{"name":"Tahaniyat Lalani","coauthored_works":96,"profile_url":"https://www.findmykol.com/kol/tahaniyat-lalani"}],"source":"works"},"presence":{"mentions":{"total":3,"shown":3,"rows":[{"url":"https://scholar.usuhs.edu/en/persons/brian-agan/","platform":"other","status":"provisional"},{"url":"https://www.usuhs.edu/profile/brian-agan-md","platform":"other","status":"provisional"},{"url":"https://www.linkedin.com/posts/hjf_covid-medicalresearch-medicalinnovation-activity-6851184539738415105-J_ZI?trk=public_profile_like_view","label":"HJF's LinkedIn post describes Brian Agan as Deputy Science Director of the IDCRP","status":"provisional"}]},"verified_means":"confirmed in more than one place; provisional means found and still being confirmed"},"recognition":{"education":{"total":1,"shown":1,"rows":[{"value":"MD, University of Colorado Medical School","source_url":"https://www.hjf.org/scientist/brian-agan","status":"verified","collected_at":"2026-11-04"}]},"roles":{"total":3,"shown":3,"rows":[{"value":"Brian Agan, MD, FIDSA (credential on 2015 journal byline)","source_url":"https://academic.oup.com/ofid/article-abstract/2/suppl_1/1072/2635325","status":"provisional","collected_at":"2026-11-04"},{"value":"Deputy Science Director and HIV Research Area Director, IDCRP","source_url":"https://www.usuhs.edu/profile/brian-agan-md","status":"verified","collected_at":"2026-11-04"},{"value":"Principal Investigator, US Military HIV Natural History Study","source_url":"https://www.usuhs.edu/profile/brian-agan-md","status":"verified","collected_at":"2026-11-04"}]},"secondary_affiliations":{"total":1,"shown":1,"rows":[{"value":"Associate Professor, Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences","source_url":"https://scholar.usuhs.edu/en/persons/brian-agan/","status":"verified","collected_at":"2026-11-04"}]},"media":{"total":2,"shown":2,"rows":[{"value":"Named as deputy science director and HIV research director in a Contagion Live article on cardiovascular disease after COVID-19","source_url":"https://www.contagionlive.com/view/cardiovascular-disease-diagnoses-remain-elevated-3-months-after-covid-19-infection","status":"provisional","collected_at":"2026-11-04"},{"value":"Named as an IDCRP collaborator in a Newswise feature on HIV gene mutations and immune recovery during therapy","source_url":"https://www.newswise.com/articles/gene-mutations-tied-to-immune-comeback-during-therapy-for-hiv-11","status":"provisional","collected_at":"2026-11-04"}]}},"similar":[{"name":"Leigh Ellis","slug":"leigh-ellis","institution":"Henry M. 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Their existence does not imply wrongdoing; CMS does not interpret these data.","coverage":"Program years 2021 onward"},"grants":{"name":"NIH RePORTER","url":"https://reporter.nih.gov","provides":"Federally funded research awards, by fiscal year","collected_at":"2026-11-04"},"congress":{"name":"OpenAlex","url":"https://openalex.org","provides":"DOI-verified congress abstracts across AACR, ASCO, ASH, ASTRO, ESMO","disclaimer":"Congress abstracts are published as DOI-bearing journal supplements and attributed via the same ORCID-disambiguated authorship as publications.","collected_at":"2026-11-04"},"publications":{"name":"PubMed (NLM)","url":"https://pubmed.ncbi.nlm.nih.gov","provides":"Peer-reviewed publications, linked to the PubMed record","collected_at":"2026-11-04"}},"methodology_url":"https://www.findmykol.com/about#methodology"}