{"schema_version":"1","generated_at":"2026-11-05T10:58:22.267Z","data_as_of":"2026-11-04","url":"https://www.findmykol.com/kol/christine-eyler","json_url":"https://www.findmykol.com/kol/christine-eyler/profile.json","record_kind":"full","profile_kind":"clinical","person":{"slug":"christine-eyler","name":"Christine Eyler","credential":"MD","title":"Butler Harris Assistant Professor in Radiation Oncology","specialty":"Radiation Oncology","specialty_raw":"Radiation Oncology","therapeutic_area":"Gastrointestinal","therapeutic_areas":["Gastrointestinal","Neuro-Oncology"],"institution":"Duke University School of Medicine","institution_url":"https://www.findmykol.com/institution/duke-university-school-of-medicine","city":"Durham","state":"NC","region":{"label":"Southeast","url":"https://www.findmykol.com/region/southeast"},"country":{"name":"United States","code":"US","status":"verified"}},"identifiers":{"npi":"1770859829","orcid":"0000-0001-6113-2478","openalex":"A5006030923"},"summary":"Christine Eyler is Butler Harris Assistant Professor in Radiation Oncology at Duke University School of Medicine. OpenAlex indexes 84 publications with 5,416 citations (h-index 25).","overview":{"text":"Christine Eyler, M.D., PH.D., is Butler Harris Assistant Professor in Radiation Oncology at Duke University School of Medicine. The public record shows 84 publications with 5,416 citations (h-index 25), centered on Esophageal Cancer Research and Treatment, Gastric Cancer Management and Outcomes, Pancreatic and Hepatic Oncology Research. It also documents 3 NIH-funded awards (2009–2026).","bullets":["Most recent indexed publication: 2026 · bioRxiv","Top research focus: Esophageal Cancer Research and Treatment"],"generated_at":"2026-11-04"},"focus":{"indications":[{"label":"Lung Cancer (NSCLC/SCLC)","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Breast Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Head & Neck Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Colorectal Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Pancreatic Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Gastroesophageal Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Sarcoma","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Neuro-Oncology / Glioma","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Hepatobiliary Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Leukemia (AML/ALL/CML/CLL)","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1},{"label":"Prostate Cancer","therapeutic_area":"Oncology","trials":0,"topics":0,"strength":1}],"research_topics":["Esophageal Cancer Research and Treatment","Gastric Cancer Management and Outcomes","Pancreatic and Hepatic Oncology Research","Glioma Diagnosis and Treatment","Cancer Cells and Metastasis"]},"scholarship":{"works_count":84,"cited_by_count":5416,"h_index":25,"i10_index":31,"pubmed_count":2,"latest_activity_year":2026,"source":"works"},"trials":{"count":0,"shown":0,"withheld":0,"rows":[],"source":"trials"},"payments":{"company_count":0,"program_years":{"first":2021,"last":null},"rows_total":0,"shown":0,"withheld":0,"rows":[],"record_url":"https://openpaymentsdata.cms.gov/search?query=1770859829","source":"payments"},"funding":{"award_count":3,"fiscal_years":{"first":2009,"last":2026},"rows_total":9,"shown":3,"withheld":6,"rows":[{"project":"K08CA263300","title":"Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform","fiscal_year":2026,"amount_usd":240760,"organization":"DUKE UNIVERSITY","source_url":"https://reporter.nih.gov/quickSearch/K08CA263300"},{"project":"R21AI193496","title":"Epigenetic mechanisms of intestinal stem cell fate conversion in response to severe radiation injury","fiscal_year":2026,"amount_usd":158616,"organization":"DUKE UNIVERSITY","source_url":"https://reporter.nih.gov/quickSearch/R21AI193496"},{"project":"K08CA263300","title":"Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform","fiscal_year":2025,"amount_usd":240767,"organization":"DUKE UNIVERSITY","source_url":"https://reporter.nih.gov/quickSearch/K08CA263300"}],"source":"grants"},"congress":{"count":23,"years":{"first":2009,"last":2026},"societies":["AACR","ASCO","ASTRO","SABCS"],"shown":3,"withheld":20,"rows":[{"title":"Abstract 7373: An integrated bioinformatic and experimental analysis of radiation-induced epigenetic reorganization in colorectal cancer","society":"AACR","meeting":"AACR Annual Meeting","year":2026,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1158/1538-7445.am2026-7373","source_url":"https://doi.org/10.1158/1538-7445.am2026-7373","status":"verified"},{"title":"Feasibility of establishing and drug screening patient-derived rectal organoid models from pretreatment rectal cancer biopsies.","society":"ASCO","meeting":"ASCO Annual Meeting","year":2023,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1200/jco.2023.41.4_suppl.176","source_url":"https://doi.org/10.1200/jco.2023.41.4_suppl.176","status":"verified"},{"title":"High Baseline TNF-α Levels may Associate with Poor Outcomes after Total Neoadjuvant Therapy for Gastroesophageal Cancer: Initial Biomarker Analysis from a Prospective Study","society":"ASTRO","meeting":"ASTRO Annual Meeting","year":2022,"role":"co_author","presentation_type":"unknown","contribution_type":"abstract","doi":"https://doi.org/10.1016/j.ijrobp.2022.07.1054","source_url":"https://doi.org/10.1016/j.ijrobp.2022.07.1054","status":"verified"}],"source":"congress"},"publications":{"total":2,"shown":2,"withheld":0,"matched_by":"ORCID record, linked to PubMed","recent":[{"title":"Alveolar Cytochrome P450 Mediates Butylated Hydroxytoluene-Induced Electrophilic Injury and Apoptosis.","year":2026,"journal":"bioRxiv : the preprint server for biology","types":["Journal Article","Preprint"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/42818751/","status":"verified"},{"title":"Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells.","year":2022,"journal":"Science translational medicine","types":["Journal Article","Research Support, N.I.H., Extramural","Research Support, Non-U.S. Gov't"],"source_url":"https://pubmed.ncbi.nlm.nih.gov/35353542/","status":"verified"}],"most_cited":{"total":84,"shown":5,"withheld":79,"rows":[{"title":"Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells","year":2009,"cited_by_count":1347,"type":"article","source_url":"https://doi.org/10.1016/j.ccr.2009.03.018"},{"title":"Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis","year":2008,"cited_by_count":737,"type":"article","source_url":"https://doi.org/10.1200/jco.2007.15.1829"},{"title":"Integrin Alpha 6 Regulates Glioblastoma Stem Cells","year":2010,"cited_by_count":660,"type":"article","source_url":"https://doi.org/10.1016/j.stem.2010.02.018"},{"title":"Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth","year":2009,"cited_by_count":333,"type":"article","source_url":"https://doi.org/10.1002/stem.188"},{"title":"Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2","year":2011,"cited_by_count":309,"type":"article","source_url":"https://doi.org/10.1016/j.cell.2011.06.006"}]},"source":"publications"},"network":{"coauthors_total":37,"shown":3,"withheld":34,"coauthors":[{"name":"Jennifer Yon-Li Wo","coauthored_works":27},{"name":"Theodore Sunki Hong","coauthored_works":25},{"name":"Jeffrey William Clark","coauthored_works":20}],"source":"works"},"recognition":{"education":{"total":2,"shown":2,"rows":[{"value":"MD, Duke University, 2012","source_url":"https://www.dukehealth.org/find-doctors-physicians/christine-e-eyler-md-phd","status":"verified","collected_at":"2026-11-04"},{"value":"PhD, Molecular Cancer Biology, Duke University, 2010","source_url":"https://www.dukehealth.org/find-doctors-physicians/christine-e-eyler-md-phd","status":"verified","collected_at":"2026-11-04"}]},"roles":{"total":1,"shown":1,"rows":[{"value":"Member, committee that develops questions for the Biology and Physics Qualifying Exam","source_url":"https://www.theabr.org/?p=31741","status":"verified","collected_at":"2026-11-04"}]},"awards":{"total":3,"shown":3,"rows":[{"value":"Strong Start Award (Physician-Scientist), Duke School of Medicine (2021)","source_url":"https://scholars.duke.edu/person/christine.eyler/recognition","status":"provisional","collected_at":"2026-11-04"},{"value":"V Foundation for Cancer Research V Scholar Award ($600,000 over three years)","source_url":"https://radonc.duke.edu/news/eyler-receives-v-foundation-scholar-award-grant","status":"verified","collected_at":"2026-11-04"},{"value":"K08 career development award","source_url":"https://radonc.duke.edu/news/eyler-awarded-k08","status":"provisional","collected_at":"2026-11-04"}]},"secondary_affiliations":{"total":3,"shown":3,"rows":[{"value":"Durham VA Health Care System (Durham, NC)","source_url":"https://www.dukehealth.org/find-doctors-physicians/christine-e-eyler-md-phd","status":"verified","collected_at":"2026-11-04"},{"value":"Member of the Duke Cancer Institute","source_url":"https://www.dukecancerinstitute.org/dci-members/christine-elissa-eyler","status":"verified","collected_at":"2026-11-04"},{"value":"Assistant Professor in Pharmacology and Cancer Biology, Duke University School of Medicine","source_url":"https://www.dukecancerinstitute.org/dci-members/christine-elissa-eyler","status":"verified","collected_at":"2026-11-04"}]},"media":{"total":1,"shown":1,"rows":[{"value":"V Foundation story \"Mothers in the Lab\" profiling Christine E. Eyler (undated)","source_url":"https://www.v.org/?p=65669","status":"verified","collected_at":"2026-11-04"}]}},"similar":[{"name":"William Kraus","slug":"william-kraus","institution":"Duke University School of Medicine","specialty":"Cardiovascular Disease","url":"https://www.findmykol.com/kol/william-kraus","json_url":"https://www.findmykol.com/kol/william-kraus/profile.json"},{"name":"Angeles Secord","slug":"angeles-secord","institution":"Duke University School of Medicine","specialty":"Gynecologic Oncology","url":"https://www.findmykol.com/kol/angeles-secord","json_url":"https://www.findmykol.com/kol/angeles-secord/profile.json"},{"name":"Virginia Kraus","slug":"virginia-kraus","institution":"Duke University School of Medicine","specialty":"Rheumatology","url":"https://www.findmykol.com/kol/virginia-kraus","json_url":"https://www.findmykol.com/kol/virginia-kraus/profile.json"},{"name":"Neal Ready","slug":"neal-ready","institution":"Duke University School of Medicine","specialty":"Medical Oncology","url":"https://www.findmykol.com/kol/neal-ready","json_url":"https://www.findmykol.com/kol/neal-ready/profile.json"},{"name":"Eric Van Cutsem","slug":"eric-cutsem","institution":"University Hospitals Leuven (UZ Leuven)","specialty":"Medical Oncology","url":"https://www.findmykol.com/kol/eric-cutsem","json_url":"https://www.findmykol.com/kol/eric-cutsem/profile.json"},{"name":"Josep Tabernero","slug":"josep-tabernero","institution":"Vall d'Hebron Institute of Oncology (VHIO)","specialty":"Medical Oncology","url":"https://www.findmykol.com/kol/josep-tabernero","json_url":"https://www.findmykol.com/kol/josep-tabernero/profile.json"},{"name":"Jaffer Ajani","slug":"jaffer-ajani","institution":"The University of Texas MD Anderson Cancer Center","specialty":"Medical Oncology","url":"https://www.findmykol.com/kol/jaffer-ajani","json_url":"https://www.findmykol.com/kol/jaffer-ajani/profile.json"},{"name":"Charles Fuchs","slug":"charles-fuchs","institution":"Tubulis GmbH","specialty":"Medical Oncology","url":"https://www.findmykol.com/kol/charles-fuchs","json_url":"https://www.findmykol.com/kol/charles-fuchs/profile.json"}],"coverage":{"note":"An identity-adjudicated profile: every section above was checked. Where a section states a count of zero, the public record was searched and nothing was found."},"not_included":{"note":"This document is the public layer: neutral facts cited to their source. Judgments (influence tier, archetype, trajectory commentary) and the itemized rows past each section's public teaser are account features and are not served here or to crawlers.","withheld_rows":{"funding":6,"congress":20,"network":34}},"sources":{"orcid":{"name":"ORCID","url":"https://orcid.org","provides":"The verified researcher identity that anchors authorship"},"identity":{"name":"NPPES (CMS)","url":"https://npiregistry.cms.hhs.gov","provides":"Identity, specialty and practice location for every U.S. clinician"},"works":{"name":"OpenAlex","url":"https://openalex.org","provides":"Citations, h-index, research topics, most-cited works and congress abstracts","collected_at":"2026-11-04"},"trials":{"name":"ClinicalTrials.gov","url":"https://clinicaltrials.gov","provides":"Investigator roles on registered clinical studies"},"payments":{"name":"CMS Open Payments","url":"https://openpaymentsdata.cms.gov","provides":"Industry payments reported to CMS, by company and program year","disclaimer":"Payments are publicly reported to CMS. Their existence does not imply wrongdoing; CMS does not interpret these data.","coverage":"Program years 2021 onward"},"grants":{"name":"NIH RePORTER","url":"https://reporter.nih.gov","provides":"Federally funded research awards, by fiscal year","collected_at":"2026-11-04"},"congress":{"name":"OpenAlex","url":"https://openalex.org","provides":"DOI-verified congress abstracts across AACR, ASCO, ASH, ASTRO, ESMO","disclaimer":"Congress abstracts are published as DOI-bearing journal supplements and attributed via the same ORCID-disambiguated authorship as publications.","collected_at":"2026-11-04"},"publications":{"name":"PubMed (NLM)","url":"https://pubmed.ncbi.nlm.nih.gov","provides":"Peer-reviewed publications, linked to the PubMed record","collected_at":"2026-11-04"}},"methodology_url":"https://www.findmykol.com/about#methodology"}