Brian Wainger, MD
Enriched profileAssociate Professor of Anesthesia, Critical Care & Pain Medicine and Neurology, Harvard Medical School; Physician-Scientist, Massachusetts General Hospital · Massachusetts General Hospital
Brian Wainger is Associate Professor of Anesthesia, Critical Care & Pain Medicine and Neurology, Harvard Medical School; Physician-Scientist, Massachusetts General Hospital at Massachusetts General Hospital. OpenAlex indexes 86 publications with 8,699 citations (h-index 29); ClinicalTrials.gov lists 4 registered studies with this person as an investigator.
Data verified 24 Aug 2026
Overview
Updated 1 Sept 2026
Brian Wainger, MD, is Associate Professor of Anesthesia, Critical Care & Pain Medicine and Neurology, Harvard Medical School at Massachusetts General Hospital / Harvard Medical School. The public record shows 86 publications with 8,699 citations (h-index 29), centered on ALS. It also documents an investigator role on 4 registered clinical trials, industry payments reported by 3 companies, 10 NIH-funded awards (2014–2026).
- Most recent indexed publication: 2026 · Nature communications
- Top research focus: ALS
- 4 registered trials on ClinicalTrials.gov
- Open Payments reporting from 3 companies
Generated from the cited public record · current as of 1 Sept 2026. Every fact links its source below.
Indications focus
from trials led + research topicsResearch focus
OpenAlex concept fingerprintWorks with
trial sponsors and companies reporting paymentsScholarship
indexed output and impact (OpenAlex)Distinct works indexed by OpenAlex, matched via ORCID; 10 in PubMed.
Total citations across indexed works.
Hirsch index, productivity × impact (OpenAlex).
Clinical & industry
trials, payments and federal fundingContact
The practice address and phone this provider lists in the federal NPPES (CMS) registry.
Practice address
Telephone
Practice address and telephone from the federal NPPES registry.
Sign in to view contact details →Clinical trials
Updated 1 Sept 2026
Listed as an investigator on 4 registered studies on ClinicalTrials.gov. The most recent:
- From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects
Sponsor: Massachusetts General Hospital
- Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
Sponsor: Brian Wainger
- Study of Sulfasalazine in Treating Painful Neuropathy
Sponsor: Massachusetts General Hospital
Industry payments
Updated 1 Sept 2026
3 companies reported payments to CMS in program years 2022–2025. These are public disclosures, not judgments. The latest:
- SPR Therapeutics, IncProgram year20251 payment
- ARGENX US, INC.Program year20231 payment
- SANOFI US SERVICES INC.Program year20221 payment
Medicare prescribing footprint (2024)
The drugs this prescriber writes for Medicare patients, grouped by drug class and therapeutic area. Every percentage is a share of their total prescribing, so you can see what they prescribe most. These are proportions, not patient counts or dollar amounts. No condition is inferred: the claims record what was prescribed, never why.
Nervous system
100%Opioid Agonist76.4%Oxycodone Hcl80%Methadone Hcl20%Part D<11 patientsCalcitonin gene-related peptide (CGRP) antagonists12.1%Aimovig Autoinjector100%Part D<11 patients
Drug classes come from the WHO ATC and U.S. National Library of Medicine (RxClass) classifications; prescribing counts come from the CMS Medicare Part D Prescribers file. Each drug is counted once, under its primary class. Medicare fee-for-service only, so no Medicare Advantage, commercial, or pediatric prescribing is included. CMS publishes this data about 17 months after the fact.
NIH funding
Updated 1 Sept 2026
10 NIH research awards on record, funded 2014–2026 per NIH RePORTER. The latest:
- Developing non-viral gene therapy for acute pain treatment
Massachusetts General Hospital
FY2026$1,130,557R61NS149953 - From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects
Massachusetts General Hospital
FY2026$758,578RM1NS128741 - Resolving the Role of Neuronal STING in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Massachusetts General Hospital
FY2026$682,793R01NS127407
Publications
Updated 1 Sept 2026
Their five most recent publications, matched to their ORCID record and linked to PubMed.
- TYK2 mediates neuroinflammation in Alzheimer's disease brains with TDP-43 pathology.
Nature communications
Article2026 - Blocking RAN translation without altering repeat RNAs rescues C9ORF72-related ALS and FTD phenotypes.
Science (New York, N.Y.)
Article2026 - TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD.
Nature neuroscience
Article2025 - Distinct modulation of calcium-activated chloride channel TMEM16A by drug-binding sites.
Proceedings of the National Academy of Sciences of the United States of America
Article2024
Online presence
Updated 1 Sept 2026
This person's own public accounts first, then places where others mention them. Two different things, listed separately.
Owned accounts
public accounts run by this person- ResearchGate
researchgate.net/scientific-contributions/Brian-J-Wainger-2006886454
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →researchgate.net ↗ - LinkedIn
linkedin.com/in/brian-wainger-34583a2a
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →linkedin.com ↗
Mentions by others
where others cite or feature them- Other
convention.bio.org/speaker/brian-wainger
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →convention.bio.org ↗ - YouTube
youtube.com/watch
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →youtube.com ↗
We list an account only when the public record ties it to this person. verified means we've confirmed the match in more than one place; provisional means it looks right but we're still confirming.
Background & recognition
Updated 1 Sept 2026
Credentials, appointments and honors, newest first, each linked to the public source it came from.
Education
degrees and training on record- A.B.
Molecular Biology, Princeton University
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →waingerlab.org ↗ - M.D./Ph.D. (ion channel physiology / neurobiology and behavior)
Columbia University College of Physicians and Surgeons
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →waingerlab.org ↗ - Board certified
Neurology, American Board of Psychiatry and Neurology
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →massgeneral.org ↗ - Subspecialty certified
Pain Medicine, American Board of Psychiatry and Neurology (ABPN)
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →massgeneral.org ↗ - Master's
Clinical and Translational Investigation, Harvard Medical School
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →worldmedicalinnovation.org ↗
Editorial & leadership roles
journal and society appointments- Principal Investigator
Wainger Laboratory, MGH Institute for Neurodegenerative Disease
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →waingerlab.org ↗ - Physician-Scientist
Sean M. Healey and AMG Center for ALS at Mass General
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →massgeneral.org ↗
Awards & honors
honors on the public record- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →worldmedicalinnovation.org ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →worldmedicalinnovation.org ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →worldmedicalinnovation.org ↗
Secondary affiliations
appointments beyond the home institution- Principal Faculty
Harvard Stem Cell Institute (HSCI)
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →hsci.harvard.edu ↗ - Associate Member
Broad Institute of MIT and Harvard
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →worldmedicalinnovation.org ↗ - Member
Harvard Program in Neuroscience / Harvard Brain Science Initiative
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →brain.harvard.edu ↗
Media & interviews
press, podcasts and appearances- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →2025.worldmedicalinnovation.org ↗
- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →youtube.com ↗
- Expanding the Understanding of ALS With New Methods: Brian Wainger
MD, PhD (NeurologyLive interview on Phase 2 ezogabine trial)
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →neurologylive.com ↗
Every item links to where we found it. verified means we've confirmed it in more than one place; provisional means we found it and are still confirming.
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