Mark Frye, MD
Enriched profileConsultant, Department of Psychiatry & Psychology, Mayo Clinic; Professor of Psychiatry, Mayo Clinic College of Medicine and Science (past Chair, Dept. of Psychiatry & Psychology, 2010-2020) · Mayo Clinic
Mark Frye is Consultant, Department of Psychiatry & Psychology, Mayo Clinic; Professor of Psychiatry, Mayo Clinic College of Medicine and Science (past Chair, Dept. of Psychiatry & Psychology, 2010-2020) at Mayo Clinic. OpenAlex indexes 760 publications with 42,160 citations (h-index 98); ClinicalTrials.gov lists 14 registered studies with this person as an investigator. By OpenAlex citation count, this profile ranks in the top 5% of Psychiatry profiles in the findmyKOL directory.
Data verified 25 Aug 2026
Overview
Updated 27 Aug 2026
Mark Frye, MD, is Consultant, Department of Psychiatry & Psychology, Mayo Clinic. The public record shows 760 publications with 42,160 citations (h-index 98), centered on Substance Use Disorders, Depression (MDD), Bipolar Disorder. It also documents an investigator role on 14 registered clinical trials, industry payments reported by 1 companies, 2 NIH-funded awards (2006–2013).
- Most recent indexed publication: 2026 · Bipolar disorders
- Top research focus: Substance Use Disorders
- 14 registered trials on ClinicalTrials.gov
- Open Payments reporting from 1 companies
Generated from the cited public record · current as of 27 Aug 2026. Every fact links its source below.
Indications focus
from trials led + research topicsResearch focus
OpenAlex concept fingerprintDrugs & molecules
across trials, industry payments and publicationsWorks with
trial sponsors and companies reporting paymentsScholarship
indexed output and impact (OpenAlex)Distinct works indexed by OpenAlex, matched via ORCID; 43 in PubMed.
Total citations across indexed works.
Hirsch index, productivity × impact (OpenAlex).
Clinical & industry
trials, payments and federal fundingContact
The practice address and phone this provider lists in the federal NPPES (CMS) registry.
Practice address
Telephone
Practice address and telephone from the federal NPPES registry.
Sign in to view contact details →Clinical trials
Updated 27 Aug 2026
Listed as an investigator on 14 registered studies on ClinicalTrials.gov. The most recent:
- Ketogenic Intervention for Bipolar Depression
Sponsor: Mayo Clinic
Industry payments
Updated 27 Aug 2026
1 company reported payments to CMS in program years 2025–2025. These are public disclosures, not judgments. The latest:
- Axsome Therapeutics, Inc.Program year20251 payment
Medicare prescribing footprint (2024)
The drugs this prescriber writes for Medicare patients, grouped by drug class and therapeutic area. Every percentage is a share of their total prescribing, so you can see what they prescribe most. These are proportions, not patient counts or dollar amounts. No condition is inferred: the claims record what was prescribed, never why.
Nervous system
100%Atypical Antipsychotic46.3%Quetiapine Fumarate48%Vraylar29%Clozapine24%Part D<11 patientsSSRI20.6%Sertraline Hcl100%Part D<11 patients
Drug classes come from the WHO ATC and U.S. National Library of Medicine (RxClass) classifications; prescribing counts come from the CMS Medicare Part D Prescribers file. Each drug is counted once, under its primary class. Medicare fee-for-service only, so no Medicare Advantage, commercial, or pediatric prescribing is included. CMS publishes this data about 17 months after the fact.
NIH funding
Updated 27 Aug 2026
2 NIH research awards on record, funded 2006–2013 per NIH RePORTER. The latest:
- Olfactory neuromodulation of visual circuits and behavior
University of California Los Angeles
FY2025$380,542R01NS120984 - Neural circuits for visual feature detection
University of California Los Angeles
FY2025$380,464R01EY026031 - Neural circuits for visual feature detection
University of California Los Angeles
FY2024$380,464R01EY026031
Publications
Updated 27 Aug 2026
Their five most recent publications, matched to their ORCID record and linked to PubMed.
- Genotype epigenome phenotype integration reveals peripheral immune contributions to type I bipolar disorder.
Nature communications
Article2026 - Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment-Related Outcomes.
Acta psychiatrica Scandinavica
Article2026
Online presence
Updated 27 Aug 2026
This person's own public accounts first, then places where others mention them. Two different things, listed separately.
Owned accounts
public accounts run by this person- Doximity
doximity.com/pub/mark-frye-md
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →doximity.com ↗ - LinkedIn
linkedin.com/in/mark-frye-9a9999116
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →linkedin.com ↗
Mentions by others
where others cite or feature them- Facebook
facebook.com/MayoClinic/posts/in-a-study-published-in-molecular-psychiatry-mark-frye-md-a-mayo-clinic-research/10158932080887517
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →facebook.com ↗ - X / Twitter
twitter.com/MayoClinic/status/199203914845929472
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →twitter.com ↗ - YouTube
youtube.com/watch
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →youtube.com ↗
We list an account only when the public record ties it to this person. verified means we've confirmed the match in more than one place; provisional means it looks right but we're still confirming.
Background & recognition
Updated 27 Aug 2026
Credentials, appointments and honors, newest first, each linked to the public source it came from.
Education
degrees and training on record- M.D.
University of Minnesota Medical School
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →mayo.edu ↗ - Board Certified
Psychiatry
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →health.usnews.com ↗
Editorial & leadership roles
journal and society appointments- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
- Director
Mayo Clinic Depression Center
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →mayo.edu ↗
Awards & honors
honors on the public record- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
Secondary affiliations
appointments beyond the home institution- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →ruralminds.org ↗
- Integrated Network for BD2 (Breakthrough Discoveries for Thriving with Bipolar Disorder)
Scientific Co-Director
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →dbsalliance.org ↗
Media & interviews
press, podcasts and appearances- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →metabolicmind.org ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →metabolicmind.org ↗
- provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →medscape.org ↗
Every item links to where we found it. verified means we've confirmed it in more than one place; provisional means we found it and are still confirming.
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