Overview
Updated 14 Jul 2026
Ralph A. DeFronzo, MD, is Professor of Medicine at UT Health San Antonio (Long School of Medicine). The public record shows 410 publications with 52,088 citations (h-index 98), centered on Diabetes Treatment and Management, Metabolism, Diabetes, and Cancer, Diabetes, Cardiovascular Risks, and Lipoproteins. It also documents an investigator role on 27 registered clinical trials, industry payments reported by 23 companies, 9 NIH-funded awards (1988–2026).
- Most recent indexed publication: 2026 · Diabetes care
- Top research focus: Diabetes Treatment and Management
- 27 registered trials on ClinicalTrials.gov
- Open Payments reporting from 23 companies
Generated from the cited public record · current as of 14 Jul 2026. Every fact links its source below.
Indications focusfrom trials led + research topics
Research focusOpenAlex concept fingerprint
Drugs & moleculesacross trials, industry payments and publications
Works withtrial sponsors and companies reporting payments
Scholarshipindexed output and impact (OpenAlex)
View publications ↓Distinct works indexed by OpenAlex, matched via ORCID; 33 in PubMed.
Total citations across indexed works.
Hirsch index (OpenAlex). i10-index 261.
Clinical & industrytrials, payments and federal funding
Clinical trials
Updated 14 Jul 2026
Listed as an investigator on 27 registered studies on ClinicalTrials.gov. The most recent:
- SGLT2i, Pioglitazone, and Ketone Production in T1D
Sponsor: The University of Texas Health Science Center at San Antonio
InvestigatorPhase 3Not, yet, recruitingNCT07056699 - SGLT2i, Pioglitazone, and Ketone Production in T2D
Sponsor: The University of Texas Health Science Center at San Antonio
InvestigatorPhase 1RecruitingNCT07053319 - SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia
Sponsor: The University of Texas Health Science Center at San Antonio
InvestigatorPhase 1RecruitingNCT07053306
Industry payments
Updated 14 Jul 2026
23 companies reported payments to CMS in program years 2021–2025. These are public disclosures, not judgments. The latest:
- Corcept TherapeuticsProgram year202523 payments$47,124openpaymentsdata.cms.gov ↗
- Regeneron Pharmaceuticals, Inc.Program year202519 payments$32,430openpaymentsdata.cms.gov ↗
- Novo Nordisk IncProgram year202510 payments$15,543openpaymentsdata.cms.gov ↗
NIH funding
Updated 14 Jul 2026
9 NIH research awards on record, funded 1988–2026 per NIH RePORTER. The latest:
- Identification of cell type-specific insulin responsive quantitative trait loci in human skeletal muscle
University of Texas Hlth Science Center
FY2026$707,781R01DK145103 - Targeting hepatic mitochondrial function in humans with NAFLD using insulin sensitizers
University of Texas Hlth Science Center
FY2026$682,149R01DK129676 - SGLT2 Inhibitors, Ketogenesis, and Ketoacidosis
University of Texas Hlth Science Center
FY2026$674,244R01DK024092
Congress activity
Updated 14 Jul 2026
2 congress contributions (2021–2022) across ASH per OpenAlex. The most recent:
- A Nonsynonymous-Single-Nucleotide Polymorphism (ns-SNP) in <i>TFPI</i>, the Gene Encoding Tissue Factor Pathway Inhibitor (TFPI), is Pleiotropically Associated with Increased Plasma TFPI Levels and a Decreased Risk of Type 2 Diabetes (T2D) in Mexican Americans of South Texas
ASH Annual Meeting
ASH2022Co-author
Published abstracts are attributed via the same ORCID-disambiguated authorship as publications, so each is DOI-verified. Podium roles (invited talks, session chairs) and oral/poster type are added as program data is confirmed.
Publications
Updated 14 Jul 2026
Their five most recent publications, matched to their ORCID record and linked to PubMed.
- Insulin Sensitive Patients With Impaired Glucose Tolerance: Physiologic and Metabolic Characterization (STOP DIABETES).
Diabetes, obesity & metabolism
2026 - Insulin resistance and hyperinsulinaemia in kidney disease: mechanisms and metabolic effects.
Nature reviews. Nephrology
2026 - How the First 9 Months Shape the Rest of Your Life: The Impact of Gestational Diabetes on the Metabolic Future.
Diabetes, obesity & metabolism
2026
Most-cited worksby citation count (OpenAlex)
- 01
- 02
- 03The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM2,473 citations1988
- 04Impaired Fasting Glucose and Impaired Glucose Tolerance1,395 citations2007
- 05Pathogenesis of type 2 diabetes mellitus1,332 citations2004
Contact
An office address from a public listing. This research profile has no federal registry record to draw from.
Office address
7703 Floyd Curl Drive, San Antonio, TX 78229
Network
Updated 14 Jul 2026
The people this person publishes with most, by number of co-authored papers. Names link to their own profile when we have one.
Background & recognition
Updated 14 Jul 2026
Credentials, appointments and honors, newest first, each linked to the public source it came from.
Educationdegrees and training on record
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗
- Board Certified
Internal Medicine and Nephrology (American Board of Internal Medicine)
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗ - Postdoctoral Fellowship in Endocrinology
NIH/Baltimore City Hospital
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗ - Postdoctoral Fellowship in Nephrology
Hospital of the University of Pennsylvania
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗
Editorial & leadership rolesjournal and society appointments
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗
Awards & honorshonors on the public record
- Prince Mahidol Award in Medicine (2022)
presented by King Maha Vajiralongkorn of Thailand, January 2023
2023verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗ - verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗
Secondary affiliationsappointments beyond the home institution
- Deputy Director
Texas Diabetes Institute, University Health System, San Antonio, TX
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗ - Holder
Joe R. and Teresa Lozano Long Distinguished Chair in Diabetes
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →news.uthscsa.edu ↗
Media & interviewspress, podcasts and appearances
- Multi-part video interview series for Diabetes in Control
including "Introduction and ADA 2017" segment
2017verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →diabetesincontrol.com ↗ - Full interview with Diabetes in Control (publisher Steve Freed) covering A1C
preferred diabetes medications, prediabetes, and beta-cell regeneration
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →diabetesincontrol.com ↗ - verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →medscape.org ↗
Every item links to where we found it. verified means we've confirmed it in more than one place; provisional means we found it and are still confirming.
Online presence
Updated 14 Jul 2026
This person's own public accounts first, then places where others mention them. Two different things, listed separately.
Owned accountspublic accounts run by this person
- Doximity
doximity.com/pub/ralph-defronzo-md
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →doximity.com ↗ - LinkedIn
linkedin.com/in/ralph-defronzo-4a56b8269
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →linkedin.com ↗ - Other
directory.uthscsa.edu/academics/profile/defronzo
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →directory.uthscsa.edu ↗
Mentions by otherswhere others cite or feature them
- Other
vumedi.com/channel/dr-ralph-defronzo/tab/videos-1536/video/obesity-and-diabetes-qa-panel-discussion
provisionalFound in a cited public source but not yet independently corroborated. Published as a labeled candidate and queued for verification.How we verify →vumedi.com ↗ - X / Twitter
x.com/asnpublications/status/1986146508232654997
- Spotify
open.spotify.com/episode/3S7LUVjBuJtgtinyAUSrX1
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →open.spotify.com ↗
We list an account only when the public record ties it to this person. verified means we've confirmed the match in more than one place; provisional means it looks right but we're still confirming.
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