Yvette Sheline, MD
Enriched profileMcLure Professor of Psychiatry and Behavioral Research; Director, Center for Neuromodulation in Depression and Stress (CNDS) · University of Pennsylvania
Yvette Sheline is McLure Professor of Psychiatry and Behavioral Research; Director, Center for Neuromodulation in Depression and Stress (CNDS) at University of Pennsylvania. OpenAlex indexes 252 publications with 31,080 citations (h-index 72); ClinicalTrials.gov lists 15 registered studies with this person as an investigator. By OpenAlex citation count, this profile ranks in the top 5% of Psychiatry profiles in the findmyKOL directory.
Data verified 25 Aug 2026
Overview
Updated 27 Aug 2026
Yvette I. Sheline, MD, is McLure Professor of Psychiatry and Behavioral Research at University of Pennsylvania, Perelman School of Medicine, Department of Psychiatry. The public record shows 252 publications with 31,080 citations (h-index 72), centered on Functional Brain Connectivity Studies, Treatment of Major Depression, Dementia and Cognitive Impairment Research. It also documents an investigator role on 15 registered clinical trials, industry payments reported by 2 companies, 10 NIH-funded awards (2013–2026).
- Most recent indexed publication: 2026 · Nature. Mental health
- Top research focus: Functional Brain Connectivity Studies
- 15 registered trials on ClinicalTrials.gov
- Open Payments reporting from 2 companies
Generated from the cited public record · current as of 27 Aug 2026. Every fact links its source below.
Indications focus
from trials led + research topicsResearch focus
OpenAlex concept fingerprintWorks with
trial sponsors and companies reporting paymentsScholarship
indexed output and impact (OpenAlex)Distinct works indexed by OpenAlex, matched via ORCID; 12 in PubMed.
Total citations across indexed works.
Hirsch index (OpenAlex). i10-index 135.
Clinical & industry
trials, payments and federal fundingContact
The practice address and phone this provider lists in the federal NPPES (CMS) registry.
Practice address
Telephone
Practice address and telephone from the federal NPPES registry.
Sign in to view contact details →Clinical trials
Updated 27 Aug 2026
Listed as an investigator on 15 registered studies on ClinicalTrials.gov. The most recent:
- A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
Sponsor: Eli Lilly and Company
- A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Sponsor: Eli Lilly and Company
- A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
Sponsor: Eli Lilly and Company
Industry payments
Updated 27 Aug 2026
2 companies reported payments to CMS in program years 2023–2025. These are public disclosures, not judgments. The latest:
- Eli Lilly and CompanyProgram year20252 payments
- Eli Lilly and CompanyProgram year20241 payment
- LivaNova USA, Inc.Program year20231 payment
NIH funding
Updated 27 Aug 2026
10 NIH research awards on record, funded 2013–2026 per NIH RePORTER. The latest:
- Reducing neural perseveration through closed loop real time fMRI neurofeedback to alleviate depressive symptoms
University of Pennsylvania
FY2026$753,942R33MH128492 - 3/4-Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)
University of Pennsylvania
FY2026$339,528R01MH128686 - HCP-2.0: Ascertaining Network Mechanisms and Analytics of Emotional Dysfunction (HARMONY)
University of Pennsylvania
FY2025$2,255,123RF1MH132962
Publications
Updated 27 Aug 2026
Their five most recent publications, matched to their ORCID record and linked to PubMed.
- Neuroimaging changes in major depression with brief computer-assisted cognitive behavioral therapy compared to waitlist.
Molecular psychiatry
Clinical Trial2025 - Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans.
Nature communications
Article2025 - Intermittent theta-burst stimulation to the right dorsolateral prefrontal cortex may increase potentiated startle in healthy individuals.
Neuropsychopharmacology
Clinical Trial2024
Most-cited works
by citation count (OpenAlex)- 01
- 02Hippocampal atrophy in recurrent major depression.Article1,927 citations1996
- 03Harmonization of cortical thickness measurements across scanners and sitesArticle1,643 citations2017
- 04The default mode network and self-referential processes in depressionArticle1,510 citations2009
- 05
Network
Updated 27 Aug 2026
The people this person publishes with most, by number of co-authored papers. Names link to their own profile when we have one.
Online presence
Updated 27 Aug 2026
This person's own public accounts first, then places where others mention them. Two different things, listed separately.
Owned accounts
public accounts run by this person- Doximity
doximity.com/pub/yvette-sheline-md
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →doximity.com ↗ - LinkedIn
linkedin.com/in/yvette-sheline-43832629
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →linkedin.com ↗ - ResearchGate
researchgate.net/profile/Yvette-Sheline-3
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →researchgate.net ↗
Mentions by others
where others cite or feature them- Other
neuroscienceresearch.wustl.edu/calendar_event/psychiatry-gr-5-20-2025-sheline
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →neuroscienceresearch.wustl.edu ↗ - X / Twitter
x.com/PennMedicine/status/1885350325411774493
We list an account only when the public record ties it to this person. verified means we've confirmed the match in more than one place; provisional means it looks right but we're still confirming.
Background & recognition
Updated 27 Aug 2026
Credentials, appointments and honors, newest first, each linked to the public source it came from.
Education
degrees and training on record- Diplomate in Psychiatry with added qualification in Geriatric Psychiatry
American Board of Psychiatry and Neurology
1991verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗ - verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗
Editorial & leadership roles
journal and society appointments- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →bbrfoundation.org ↗
Awards & honors
honors on the public record- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →bbrfoundation.org ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →bbrfoundation.org ↗
- verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →bbrfoundation.org ↗
Secondary affiliations
appointments beyond the home institution- Secondary faculty appointment
Department of Neurology, Perelman School of Medicine, University of Pennsylvania
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗ - Director
Center for Neuromodulation in Depression and Stress (CNDS), University of Pennsylvania
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗ - Section Director
Mood, Anxiety and Trauma, Department of Psychiatry, University of Pennsylvania
verifiedCorroborated by findmyKOL. We matched this record across two or more independent public sources (or a verified ORCID / NPI identifier bridge) before attributing it to this person.How we verify →med.upenn.edu ↗
Every item links to where we found it. verified means we've confirmed it in more than one place; provisional means we found it and are still confirming.
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