Clinical trialNCT00000534CompletedPhase 3Interventional

Calcium for Pre-Eclampsia Prevention (CPEP)

SponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Cardiovascular DiseasesEclampsiaHELLP SyndromeHeart DiseasesHypertensionPre-Eclampsia+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the efficacy of 2 grams per day of oral calcium supplementation in reducing the combined incidence of hypertensive disorders of pregnancy: pre-eclampsia, eclampsia, and the HELLP Syndrome (hypertension, thrombocytopenia, hemolysis, and abnormal liver function). The National Institute of Child Health and Human Development (NICHD) initiated the trial in 1991, with joint funding provided by the National Heart, Lung, and Blood Institute in fiscal years 1992, 1993, and 1995.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Baha Sibai
University of Tennessee
KOL profile →
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Cynthia Morris
Oregon Health and Science University
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John Hauth
University of Alabama at Birmingham
KOL profile →
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Luis Curet
University of New Mexico
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Patrick Catalano
Case Western Reserve University
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Calcium

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Mar 1991
Primary completion: —
Completion: 30 Jun 2000
Last update posted: 13 Mar 2017
Registered enrollment: —
Registry id: NCT00000534

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Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.