Clinical trialNCT00001091CompletedPhase 1Interventional

Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment200HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to see if it is safe and effective to give HIV-infected children and teens 1 of 4 anti-HIV drug combinations. Decreasing HIV levels in infected patients can slow down disease progression. Further study is needed to find out which drug combinations are most effective in doing this.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Andrew Wiznia
Study Chair
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George Johnson
Study Chair
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Paul Krogstad
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

55 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

Ramon Ruiz Arnau Univ Hosp / Pediatrics
Bayamón, Puerto Rico
San Juan City Hosp
San Juan, Puerto Rico

United States

Univ of Alabama at Birmingham - Pediatric
Birmingham, Alabama, United States
Ucsd Med Ctr / Pediatrics / Clinical Sciences
La Jolla, California, United States
Long Beach Memorial (pediatric)
Long Beach, California, United States
Children'S Hosp of Los Angeles/ucla Med Ctr
Los Angeles, California, United States
Harbor - Ucla Med Ctr / Ucla School of Medicine
Los Angeles, California, United States
Los Angeles County - Usc Med Ctr
Los Angeles, California, United States
Ucla Med Ctr / Pediatric
Los Angeles, California, United States
Children'S Hosp of Oakland
Oakland, California, United States
Ucsf / Moffitt Hosp - Pediatric
San Francisco, California, United States
Connecticut Children'S Med Ctr - Pediatric
Hartford, Connecticut, United States
Yale Univ Med School
New Haven, Connecticut, United States
Children'S Hosp of Washington Dc
Washington D.C., District of Columbia, United States
Howard Univ Hosp
Washington D.C., District of Columbia, United States
Washington Hosp Ctr
Washington D.C., District of Columbia, United States
North Broward Hosp District
Fort Lauderdale, Florida, United States
Univ of Florida Gainesville
Gainesville, Florida, United States
Univ of Florida Health Science Ctr / Pediatrics
Jacksonville, Florida, United States
Palm Beach County Health Dept
Riviera Beach, Florida, United States
Emory Univ Hosp / Pediatrics
Atlanta, Georgia, United States
Med College of Georgia
Augusta, Georgia, United States
Chicago Children'S Memorial Hosp
Chicago, Illinois, United States
Cook County Hosp
Chicago, Illinois, United States
Univ of Chicago Children'S Hosp
Chicago, Illinois, United States
Univ of Illinois College of Medicine / Pediatrics
Chicago, Illinois, United States
Tulane Univ / Charity Hosp of New Orleans
New Orleans, Louisiana, United States
Johns Hopkins Hosp - Pediatric
Baltimore, Maryland, United States
Univ of Maryland at Baltimore / Univ Med Ctr
Baltimore, Maryland, United States
Baystate Med Ctr of Springfield
Springfield, Massachusetts, United States
Univ of Massachusetts Med School
Worcester, Massachusetts, United States
Univ of Mississippi Med Ctr
Jackson, Mississippi, United States
Umdnj - Robert Wood Johnson Med School / Pediatrics
New Brunswick, New Jersey, United States
Saint Joseph'S Hosp and Med Ctr/umdnj - New Jersey Med Schl
Newark, New Jersey, United States
King'S County Hosp Ctr / Pediatrics
Brooklyn, New York, United States
Suny - Brooklyn
Brooklyn, New York, United States
North Shore Univ Hosp
Great Neck, New York, United States
Schneider Children'S Hosp
New Hyde Park, New York, United States
Bellevue Hosp / New York Univ Med Ctr
New York, New York, United States
Columbia Presbyterian Med Ctr
New York, New York, United States

15 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Lamivudine →Nelfinavir →Nevirapine →Ritonavir →Stavudine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: —
Primary completion: —
Completion: 31 Oct 2000
Last update posted: 4 Nov 2021
Registered enrollment: 200
Registry id: NCT00001091

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.