Clinical trialNCT00001125CompletedPhase 1Interventional

Use of a Varicella-Zoster Virus (VZV) Vaccine to Prevent Shingles in HIV-Infected Children Who Have Already Had Chickenpox

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment60ChickenpoxHIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to see if the varicella-zoster virus (VZV) vaccine will be safe and if it can help prevent shingles in HIV-infected children who have already had chickenpox. VZV is the virus that causes chickenpox. If this virus is reactivated in the body, it can also cause shingles. Shingles is common in children with HIV who have had chickenpox, although it is usually not life-threatening. The VZV vaccine used in this study may be able to prevent HIV-positive children who have had chickenpox from developing shingles.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Anne Gershon
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

22 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Long Beach Memorial Med. Ctr., Miller Children'S Hosp.
Long Beach, California, United States
Ucla-Los Angeles/brazil Aids Consortium (labac) Crs
Los Angeles, California, United States
Usc la Nichd Crs
Los Angeles, California, United States
Harbor - Ucla Med. Ctr. - Dept. of Peds., Div. of Infectious Diseases
Torrance, California, United States
South Florida Cdtc Ft Lauderdale Nichd Crs
Fort Lauderdale, Florida, United States
Univ. of Florida Jacksonville Nichd Crs
Jacksonville, Florida, United States
Univ. of Miami Ped. Perinatal Hiv/aids Crs
Miami, Florida, United States
Bmc, Div. of Ped Infectious Diseases
Boston, Massachusetts, United States
Hms - Children'S Hosp. Boston, Div. of Infectious Diseases
Boston, Massachusetts, United States
Baystate Health, Baystate Med. Ctr.
Springfield, Massachusetts, United States
Cooper Univ. Hosp.
Camden, New Jersey, United States
Nj Med. School Crs
Newark, New Jersey, United States
Columbia Impaact Crs
New York, New York, United States
Cornell Univ., Div. of Ped. Infectious Diseases & Immunology
New York, New York, United States
Harlem Hosp. Ctr. Ny Nichd Crs
New York, New York, United States
Nyu Ny Nichd Crs
New York, New York, United States
Strong Memorial Hospital Rochester Ny Nichd Crs
Rochester, New York, United States
Suny Upstate Med. Univ., Dept. of Peds.
Syracuse, New York, United States
St. Christopher'S Hosp. for Children
Philadelphia, Pennsylvania, United States
the Children'S Hosp. of Philadelphia Impaact Crs
Philadelphia, Pennsylvania, United States
St. Jude/uthsc Crs
Memphis, Tennessee, United States
Vanderbilt Univ. Med. Ctr., Div. of Ped. Infectious Diseases
Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

VARICELLA VIRUS VACCINE,LIVE

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: —
Primary completion: —
Completion: 31 Mar 2004
Last update posted: 1 Nov 2021
Registered enrollment: 60
Registry id: NCT00001125

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Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.