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Clinical trialNCT00002493CompletedPhase 3Interventional

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer

SponsorGynecologic Oncology GroupEndometrial CancerPsychosocial Effects of Cancer and Its Treatment
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which treatment regimen is more effective for endometrial cancer. PURPOSE: Randomized phase III trial to compare radiation therapy with chemotherapy in treating patients who have advanced endometrial cancer.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

58 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama Comprehensive Cancer Center

    Birmingham, Alabama, United States

  • Ccop - Greater Phoenix

    Phoenix, Arizona, United States

  • Jonsson Comprehensive Cancer Center, Ucla

    Los Angeles, California, United States

  • Usc/norris Comprehensive Cancer Center

    Los Angeles, California, United States

  • Chao Family Comprehensive Cancer Center

    Orange, California, United States

  • Women'S Cancer Center

    Palo Alto, California, United States

  • Stanford University Medical Center

    Stanford, California, United States

  • University of Colorado Cancer Center

    Denver, Colorado, United States

  • Vincent T. Lombardi Cancer Research Center, Georgetown University

    Washington D.C., District of Columbia, United States

  • Walter Reed Army Medical Center

    Washington D.C., District of Columbia, United States

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, United States

  • Ccop - Atlanta Regional

    Atlanta, Georgia, United States

  • Emory University Hospital - Atlanta

    Atlanta, Georgia, United States

  • Mbccop - Hawaii

    Honolulu, Hawaii, United States

  • Rush-Presbyterian-St. Luke'S Medical Center

    Chicago, Illinois, United States

  • University of Chicago Cancer Research Center

    Chicago, Illinois, United States

  • Indiana University Cancer Center

    Indianapolis, Indiana, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, United States

  • Albert B. Chandler Medical Center, University of Kentucky

    Lexington, Kentucky, United States

  • Johns Hopkins Oncology Center

    Baltimore, Maryland, United States

  • University of Massachusetts Memorial Medical Center

    Worcester, Massachusetts, United States

  • Ccop - Ann Arbor Regional

    Ann Arbor, Michigan, United States

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, United States

  • University of Minnesota Cancer Center

    Minneapolis, Minnesota, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, United States

  • Ccop - Kansas City

    Kansas City, Missouri, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Ccop - Missouri Valley Cancer Consortium

    Omaha, Nebraska, United States

  • Ccop - Southern Nevada Cancer Research Foundation

    Las Vegas, Nevada, United States

  • Cooper Hospital/university Medical Center

    Camden, New Jersey, United States

  • Cancer Center of Albany Medical Center

    Albany, New York, United States

  • State University of New York Health Science Center at Brooklyn

    Brooklyn, New York, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, United States

  • University of Rochester Cancer Center

    Rochester, New York, United States

  • State University of New York Health Sciences Center - Stony Brook

    Stony Brook, New York, United States

  • Lineberger Comprehensive Cancer Center, Unc

    Chapel Hill, North Carolina, United States

  • Duke Comprehensive Cancer Center

    Durham, North Carolina, United States

  • Brookview Research, Inc.

    Winston-Salem, North Carolina, United States

  • Comprehensive Cancer Center of Wake Forest University Baptist Medical Center

    Winston-Salem, North Carolina, United States

  • Barrett Cancer Center, the University Hospital

    Cincinnati, Ohio, United States

18 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 May 1992
Primary completion
30 Apr 2001
Completion
—
Last update posted
14 Feb 2014
Registered enrollment
—
Registry id
NCT00002493

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.