Clinical trialNCT00002527CompletedPhase 3Interventional

Aspirin in Treating Patients With Colorectal Cancer That Has Been Surgically Removed

SponsorAlliance for Clinical Trials in OncologyEnrollment635Colorectal Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of aspirin may be an effective way to prevent the recurrence of polyps in colorectal cancer. PURPOSE: Randomized phase III trial to study the effectiveness of aspirin in treating patients who have stage I, stage II, or stage III colorectal cancer that has been surgically removed.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Robert Sandler, MD, MPH
UNC Lineberger Comprehensive Cancer Center
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

42 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Saskatchewan Cancer Agency
Regina, Saskatchewan, Canada

United States

Ccop - Scottsdale Oncology Program
Scottsdale, Arizona, United States
Ucsf Cancer Center and Cancer Research Institute
San Francisco, California, United States
Ccop - Mount Sinai Medical Center
Miami Beach, Florida, United States
University of Chicago Cancer Research Center
Chicago, Illinois, United States
Ccop - Illinois Oncology Research Association
Peoria, Illinois, United States
Ccop - Carle Cancer Center
Urbana, Illinois, United States
Ccop - Cedar Rapids Oncology Project
Cedar Rapids, Iowa, United States
Ccop - Iowa Oncology Research Association
Des Moines, Iowa, United States
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Siouxland Hematology-Oncology
Sioux City, Iowa, United States
Ccop - Ochsner
New Orleans, Louisiana, United States
Marlene & Stewart Greenebaum Cancer Center, University of Maryland
Baltimore, Maryland, United States
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States
University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, United States
Ccop - Ann Arbor Regional
Ann Arbor, Michigan, United States
University of Minnesota Cancer Center
Minneapolis, Minnesota, United States
Mayo Clinic Cancer Center
Rochester, Minnesota, United States
Centracare Clinic
Saint Cloud, Minnesota, United States
Ellis Fischel Cancer Center - Columbia
Columbia, Missouri, United States
Barnes-Jewish Hospital
St Louis, Missouri, United States
Ccop - Missouri Valley Cancer Consortium
Omaha, Nebraska, United States
Ccop - Southern Nevada Cancer Research Foundation
Las Vegas, Nevada, United States
Norris Cotton Cancer Center
Lebanon, New Hampshire, United States
Roswell Park Cancer Institute
Buffalo, New York, United States
Ccop - North Shore University Hospital
Manhasset, New York, United States
New York Presbyterian Hospital - Cornell Campus
New York, New York, United States
State University of New York - Upstate Medical University
Syracuse, New York, United States
Lineberger Comprehensive Cancer Center, Unc
Chapel Hill, North Carolina, United States
Ccop - Southeast Cancer Control Consortium
Winston-Salem, North Carolina, United States
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, United States
Quain & Ramstad Clinic, P.C.
Bismarck, North Dakota, United States
Ccop - Merit Care Hospital
Fargo, North Dakota, United States
Altru Health Systems
Grand Forks, North Dakota, United States
Ccop - Toledo Community Hospital Oncology Program
Toledo, Ohio, United States
Ccop - Geisinger Clinical and Medical Center
Danville, Pennsylvania, United States
Rhode Island Hospital
Providence, Rhode Island, United States
Rapid City Regional Hospital
Rapid City, South Dakota, United States
Ccop - Sioux Community Cancer Consortium
Sioux Falls, South Dakota, United States
University of Tennessee, Memphis Cancer Center
Memphis, Tennessee, United States

2 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Aspirin →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 1993
Primary completion: 31 Mar 2003
Completion: 31 Jan 2006
Last update posted: 4 Jul 2016
Registered enrollment: 635
Registry id: NCT00002527

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.