Clinical trialNCT00002550CompletedPhase 3Interventional

Chemotherapy Plus Radiation Therapy With or Without Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

SponsorRadiation Therapy Oncology GroupEnrollment429Lung Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet known if chemotherapy plus radiation therapy is more effective with or without surgery for lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of combining cisplatin, etoposide, and radiation therapy with or without surgery in treating patients who have stage IIIA non-small cell lung cancer.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Bruce E. Johnson, MD
Dana-Farber Cancer Institute
Study Chair
clinicaltrials.gov ↗
David H. Johnson, MD
Vanderbilt-Ingram Cancer Center
Study ChairKOL profile →
clinicaltrials.gov ↗
David S. Ettinger, MD
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Study Chair
clinicaltrials.gov ↗
Kathy S. Albain, MD
Loyola University
Principal Investigator
clinicaltrials.gov ↗
Mark R. Green, MD
Medical University of South Carolina
Study Chair
clinicaltrials.gov ↗
Robert C. Miller, MD
Mayo Clinic
Study Chair
clinicaltrials.gov ↗
Yvon Cormier, MD
L'Hopital Laval
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

South Africa

Pretoria Academic Hospitals
Pretoria, South Africa

United States

Ccop - Carle Cancer Center
Urbana, Illinois, United States
Indiana University Cancer Center
Indianapolis, Indiana, United States
Veterans Affairs Medical Center - Indianapolis (roudebush)
Indianapolis, Indiana, United States
Ccop - Cedar Rapids Oncology Project
Cedar Rapids, Iowa, United States
Ccop - Ann Arbor Regional
Ann Arbor, Michigan, United States
Ccop - Missouri Valley Cancer Consortium
Omaha, Nebraska, United States
University of Rochester Cancer Center
Rochester, New York, United States
Ireland Cancer Center
Cleveland, Ohio, United States
Ccop - Toledo Community Hospital Oncology Program
Toledo, Ohio, United States
Hahnemann University Hospital
Philadelphia, Pennsylvania, United States
University of Pittsburgh Cancer Institute
Pittsburgh, Pennsylvania, United States
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States
Ccop - Green Bay
Green Bay, Wisconsin, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Veterans Affairs Medical Center - Milwaukee (zablocki)
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cisplatin →Etoposide →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Mar 1994
Primary completion: 30 Jun 2004
Completion: 30 Nov 2013
Last update posted: 17 Nov 2015
Registered enrollment: 429
Registry id: NCT00002550

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.