Clinical trialNCT00002622CompletedPhase 3Interventional

Talc in Treating Patients With Malignant Pleural Effusion

SponsorAlliance for Clinical Trials in OncologyEnrollment501Metastatic Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Talc may relieve malignant pleural effusion. It is not yet known whether wet talc is more effective than dry talc in treating patients with malignant pleural effusion. PURPOSE: Randomized phase III trial to compare the effectiveness of wet talc with dry talc in treating patients with malignant pleural effusion.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jemi Olak, MD
Kern Medical Center
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

241 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Tom Baker Cancer Center - Calgary
Calgary, Alberta, Canada
Cross Cancer Institute
Edmonton, Alberta, Canada
British Columbia Cancer Agency - Vancouver Island Cancer Centre
Victoria, British Columbia, Canada
Doctor Leon Richard Oncology Centre
Moncton, New Brunswick, Canada
Saint John Regional Hospital
Saint John, New Brunswick, Canada
Nova Scotia Cancer Centre
Halifax, Nova Scotia, Canada
Northeastern Ontario Regional Cancer Centre, Sudbury
Greater Sudbury, Ontario, Canada
Cancer Care Ontario-Hamilton Regional Cancer Centre
Hamilton, Ontario, Canada
Kingston Regional Cancer Centre
Kingston, Ontario, Canada
Cancer Care Ontario-London Regional Cancer Centre
London, Ontario, Canada
Ottawa Regional Cancer Centre - Civic Campus
Ottawa, Ontario, Canada
Northwestern Ontario Regional Cancer Centre, Thunder Bay
Thunder Bay, Ontario, Canada
Princess Margaret Hospital
Toronto, Ontario, Canada
Centre Hospitalier de L'Universite de Montreal
Montreal, Quebec, Canada
Mcgill University Department of Oncology
Montreal, Quebec, Canada
Saskatchewan Cancer Agency
Regina, Saskatchewan, Canada
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada

United States

University of Alabama Comprehensive Cancer Center
Birmingham, Alabama, United States
Veterans Affairs Medical Center - Birmingham
Birmingham, Alabama, United States
Huntsville Hospital System
Huntsville, Alabama, United States
Mbccop - University of South Alabama
Mobile, Alabama, United States
Urology Associates - Mobile Al
Mobile, Alabama, United States
Alabama Oncology, Llc
Montgomery, Alabama, United States
Radiation Oncology Associates of West Alabama
Tuscallosa, Alabama, United States
Providence Cancer Therapy Center
Anchorage, Alaska, United States
Ccop - Scottsdale Oncology Program
Scottsdale, Arizona, United States
Arizona Cancer Center
Tucson, Arizona, United States
Providence Saint Joseph Medical Center - Burbank
Burbank, California, United States
Mount Diablo Medical Center
Concord, California, United States
Beckman Research Institute, City of Hope
Duarte, California, United States
California Cancer Center
Fresno, California, United States
Saint Agnes Cancer Center
Fresno, California, United States
Glendale Memorial Hospital and Health Center
Glendale, California, United States
Sutter Health Western Division Cancer Research Group
Greenbrae, California, United States
Loma Linda University Medical Center
Loma Linda, California, United States
Veterans Affairs Medical Center - Long Beach
Long Beach, California, United States
Jonsson Comprehensive Cancer Center, Ucla
Los Angeles, California, United States
Kaiser Permanente Medical Center - Los Angeles
Los Angeles, California, United States
Usc/norris Comprehensive Cancer Center
Los Angeles, California, United States
Veterans Affairs Outpatient Clinic - Martinez
Martinez, California, United States

201 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Talc

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Dec 1994
Primary completion: 31 Mar 2005
Completion: 31 Jan 2006
Last update posted: 28 Jun 2016
Registered enrollment: 501
Registry id: NCT00002622

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.