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Clinical trialNCT00002766CompletedPhase 3Interventional

Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma

SponsorMemorial Sloan Kettering Cancer CenterEnrollment170LeukemiaLymphoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is more effective for acute lymphoblastic leukemia, lymphoblastic lymphoma, or chronic myelogenous leukemia. PURPOSE: This randomized phase III trial is studying two different chemotherapy regimens and comparing them to see how well they work in treating adults with acute lymphoblastic leukemia, lymphoblastic lymphoma, or chronic myelogenous leukemia.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Jonsson Comprehensive Cancer Center, Ucla

    Los Angeles, California, United States

  • Stanford Cancer Center at Stanford University Medical Center

    Stanford, California, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, United States

  • New York Medical College

    Valhalla, New York, United States

  • Duke Comprehensive Cancer Center

    Durham, North Carolina, United States

  • Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CarmustineCyclophosphamide →Cytarabine →DactinomycinDaunorubicin →Doxorubicin →Etoposide →Mercaptopurine →Methotrexate →Mitoxantrone →Pegaspargase →Prednisone →Sargramostim →Vincristine →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Mar 1996
Primary completion
30 Sept 2011
Completion
30 Sept 2011
Last update posted
22 Feb 2016
Registered enrollment
170
Registry id
NCT00002766
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.