Clinical trialNCT00003407WithdrawnPhase 2Interventional

Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML

SponsorRush University Medical CenterEnrollment0Drug/Agent Toxicity by Tissue/OrganLeukemiaMyelodysplastic SyndromesNeutropenia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of amifostine and high-dose combination chemotherapy in treating patients with acute myeloid leukemia or chronic myelogenous leukemia.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Philip D. Bonomi, MD
Rush University Medical Center
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Angelo P. Creticos, M.D. Cancer Center
Chicago, Illinois, United States
Cook County Hospital
Chicago, Illinois, United States
Rush Cancer Institute
Chicago, Illinois, United States
Rush-Riverside Cancer Center
Kankakee, Illinois, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Amifostine →Cytarabine →Mitoxantrone →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 13 Feb 2001
Primary completion: 7 Apr 2004
Completion: 7 Apr 2004
Last update posted: 2 Feb 2023
Registered enrollment: 0
Registry id: NCT00003407

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.