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Clinical trialNCT00003671CompletedPhase 2Interventional

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia

SponsorChildren's Oncology GroupEnrollment59Leukemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating children who have newly diagnosed acute lymphocytic leukemia.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

57 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Alberta Children'S Hospital

    Calgary, Alberta, Canada

  • Children'S Hospital of Eastern Ontario

    Ottawa, Ontario, Canada

  • Montreal Children'S Hospital

    Montreal, Quebec, Canada

  • Centre Hospitalier de L'Universite Laval

    Sainte-Foy, Quebec, Canada

Netherlands
  • Academisch Ziekenhuis Groningen

    Groningen, Netherlands

Puerto Rico
  • San Jorge Childrens Hospital

    Santurce, Puerto Rico

Switzerland
  • Clinique de Pediatrie

    Geneva, Switzerland

United States
  • Arizona Cancer Center

    Tucson, Arizona, United States

  • Lucile Packard Children'S Hospital at Stanford

    Palo Alto, California, United States

  • Sutter Cancer Center

    Sacramento, California, United States

  • Kaiser Permanente-Southern California Permanente Medical Group

    San Diego, California, United States

  • Naval Medical Center - San Diego

    San Diego, California, United States

  • Kaiser Permanente Medical Center - Santa Clara

    Santa Clara, California, United States

  • Nemours Children'S Clinic

    Jacksonville, Florida, United States

  • Baptist Hospital of Miami

    Miami, Florida, United States

  • Sylvester Cancer Center, University of Miami

    Miami, Florida, United States

  • Walt Disney Memorial Cancer Institute

    Orlando, Florida, United States

  • St. Mary'S Hospital

    West Palm Beach, Florida, United States

  • Emory University Hospital - Atlanta

    Atlanta, Georgia, United States

  • Tripler Army Medical Center

    Honolulu, Hawaii, United States

  • Children'S Memorial Hospital, Chicago

    Chicago, Illinois, United States

  • Rush-Presbyterian-St. Luke'S Medical Center

    Chicago, Illinois, United States

  • Christ Hospital

    Oak Lawn, Illinois, United States

  • Saint Jude Midwest Affiliate

    Peoria, Illinois, United States

  • Via Christi Regional Medical Center-Saint Francis Campus

    Wichita, Kansas, United States

  • Tulane University School of Medicine

    New Orleans, Louisiana, United States

  • Eastern Maine Medical Center

    Bangor, Maine, United States

  • Maine Children'S Cancer Program

    Portland, Maine, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, United States

  • St. John'S Hospital and Medical Center

    Detroit, Michigan, United States

  • Hurley Medical Center

    Flint, Michigan, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, United States

  • Keesler Medical Center - Keesler Afb

    Keesler Air Force Base, Mississippi, United States

  • University of Missouri-Columbia Hospital and Clinics

    Columbia, Missouri, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Norris Cotton Cancer Center

    Lebanon, New Hampshire, United States

  • University of New Mexico School of Medicine

    Albuquerque, New Mexico, United States

  • State University of New York Health Sciences Center - Stony Brook

    Stony Brook, New York, United States

  • Duke Comprehensive Cancer Center

    Durham, North Carolina, United States

  • Oklahoma Memorial Hospital

    Oklahoma City, Oklahoma, United States

17 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AsparaginaseCyclophosphamideCytarabineDaunorubicinDexamethasoneLeucovorinMercaptopurineMethotrexateThioguanineVincristine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 1998
Primary completion
30 Nov 2002
Completion
28 Feb 2009
Last update posted
25 Jul 2014
Registered enrollment
59
Registry id
NCT00003671

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.