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Clinical trialNCT00003894CompletedPhase 2Interventional

Thalidomide in Treating Patients With Chronic Graft-Versus-Host Disease Following Bone Marrow Transplant

SponsorRoswell Park Cancer InstituteEnrollment36Graft Versus Host DiseaseUnspecified Adult Solid Tumor, Protocol SpecificUnspecified Childhood Solid Tumor, Protocol Specific
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Thalidomide may interfere with the body's ability to recognize transplanted bone marrow cells as foreign and may help treat patients with graft-versus-host disease. PURPOSE: Randomized phase II trial to study the effectiveness of thalidomide in treating patients who have chronic graft-versus-host disease following bone marrow transplantation.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, United States

  • Louisiana State University School of Medicine

    New Orleans, Louisiana, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, United States

  • Simmons Cancer Center - Dallas

    Dallas, Texas, United States

  • Brooke Army Medical Center

    Fort Sam Houston, Texas, United States

  • Cook Children'S Medical Center - Fort Worth

    Fort Worth, Texas, United States

  • University of Texas - Md Anderson Cancer Center

    Houston, Texas, United States

  • Cancer Center of the Medical College of Wisconsin

    Milwaukee, Wisconsin, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Thalidomide →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Mar 1999
Primary completion
31 Jan 2000
Completion
30 Jun 2002
Last update posted
7 Mar 2011
Registered enrollment
36
Registry id
NCT00003894
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.