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Clinical trialNCT00004204UnknownPhase 2Interventional

Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma

SponsorHerbert Irving Comprehensive Cancer CenterBrain and Central Nervous System Tumors
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of temozolomide in treating patients who have recurrent or progressive malignant glioma.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Stanford University Medical Center

    Stanford, California, United States

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida, United States

  • Robert H. Lurie Comprehensive Cancer Center, Northwestern University

    Chicago, Illinois, United States

  • Cancer Center of Albany Medical Center

    Albany, New York, United States

  • Herbert Irving Comprehensive Cancer Center

    New York, New York, United States

  • Nalitt Institute for Cancer and Blood Related Diseases

    Staten Island, New York, United States

  • Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio, United States

  • Neurological Clinic

    Portland, Oregon, United States

  • University of Pennsylvania Cancer Center

    Philadelphia, Pennsylvania, United States

  • Froedtert Memorial Lutheran Hospital

    Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Feb 2000
Primary completion
—
Completion
—
Last update posted
6 Jan 2014
Registered enrollment
—
Registry id
NCT00004204

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.