Clinical trialNCT00005009TerminatedPhase 1Interventional

Evaluation of the Safety of Varivax® in Pediatric Renal Transplant Recipients

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment7Kidney Transplant Recipients

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to find out whether Varivax is safe for use in children with kidney transplants and whether it protects children from serious infection. Varivax is a vaccine against varicella zoster virus (VZV), the virus that causes chickenpox (varicella) and shingles (zoster). Healthy children are already receiving Varivax shots to protect them from chickenpox. Few children with kidney transplants have received Varivax because doctors have been concerned that Varivax might cause serious reactions in them. On the other hand, VZV infection can be a life-threatening disease in these children. For this reason, doctors ultimately want to learn whether Varivax might safely prevent VZV infections in children who have had kidney transplants.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Amir Tejani, MD
North American Pediatric Renal Transplantation Study (NAPRTCS)
Study Chair
clinicaltrials.gov ↗
Beverly L. Connelly, MD
Vaccine and Treatment Evaluation Unit (VTEU)-Cincinnati Children's
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham - Vaccine and Treatment Evaluation Unit (vteu)
Birmingham, Alabama, United States
Boston Children'S Hospital - Vaccine and Treatment Evaluation Unit (vteu)
Boston, Massachusetts, United States
University of Michigan - Vaccine and Treatment Evaluation Unit (vteu)
Ann Arbor, Michigan, United States
University of Texas Health Science Center at San Antonio - Vaccine and Treatment Evaluation Unit (vteu)
San Antonio, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Varivax® →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Feb 1998
Primary completion: 16 Jun 2001
Completion: 16 Jun 2001
Last update posted: 16 Feb 2017
Registered enrollment: 7
Registry id: NCT00005009

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.