Clinical trialNCT00005133Active, not recruitingObservational

Cardiovascular Health Study (CHS)

SponsorNational Heart, Lung, and Blood Institute (NHLBI)Enrollment5,888Cardiovascular DiseasesCerebrovascular AccidentCoronary DiseaseDiabetes MellitusHeart DiseasesHeart Failure, Congestive+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To determine the extent to which known risk factors predict coronary heart disease and stroke in the elderly, to assess the precipitants of coronary heart disease and stroke in the elderly, and to identify the predictors of mortality and functional impairments in clinical coronary disease or stroke.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Anne B. Newman, MD MPH
University of Pittsburgh
Principal Investigator
clinicaltrials.gov ↗
Bruce M. Psaty, MD PhD
University of Washington
Principal Investigator
clinicaltrials.gov ↗
Calvin H. Hirsch, MD
University of California, Davis
Principal Investigator
clinicaltrials.gov ↗
Mary F. Lyles, MD
Bowman Gray School of Medicine
Principal Investigator
clinicaltrials.gov ↗
Michelle Carlson, PhD
Johns Hopkins University
Principal Investigator
clinicaltrials.gov ↗
Russell Tracy, PhD
University of Vermont
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California, Davis
Sacramento, California, United States
Johns Hopkins University
Hagerstown, Maryland, United States
Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
University of Vermont
Colchester, Vermont, United States
University of Washington
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 1988
Primary completion: 31 Dec 2027
Completion: 31 Dec 2027
Last update posted: 3 Feb 2026
Registered enrollment: 5,888
Registry id: NCT00005133

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.