Clinical trialNCT00011479CompletedPhase 1Interventional

Blood Levels of Abacavir After One Dose in HIV-Infected Children and Adolescents

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment24HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to measure blood levels of abacavir in children and adolescents over a period of time following a single dose so that a dosage for adolescents can be determined. Little is known about how abacavir is cleared by the body in adolescents. It has been shown that young children require a higher abacavir dose based on weight than adults. Older children, or adolescents, may not require as high a dose. This study may provide information as to whether the children's dose or the adult dose is better for HIV-infected adolescents.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

John Rodman
Study Chair
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Lawrence D'Angelo
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

24 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Univ of Alabama at Birmingham - Pediatric
Birmingham, Alabama, United States
Children'S Hospital of L.A. (pediatric)
Los Angeles, California, United States
Los Angeles County - Usc Med Ctr
Los Angeles, California, United States
Univ of California, San Diego
San Diego, California, United States
Children'S Hosp of Washington Dc
Washington D.C., District of Columbia, United States
Univ of Florida Health Science Ctr / Pediatrics
Jacksonville, Florida, United States
Univ of Miami (pediatric)
Miami, Florida, United States
Med College of Georgia
Augusta, Georgia, United States
the Med Ctr Inc
Columbus, Georgia, United States
Chicago Children'S Memorial Hosp
Chicago, Illinois, United States
Cook County Hosp
Chicago, Illinois, United States
Univ of Chicago Children'S Hosp
Chicago, Illinois, United States
Children'S Hosp of Boston
Boston, Massachusetts, United States
Univ of Medicine & Dentistry of New Jersey / Univ Hosp
Newark, New Jersey, United States
Metropolitan Hosp Ctr
New York, New York, United States
Univ of Rochester Med Ctr
Rochester, New York, United States
State Univ of New York at Stony Brook
Stony Brook, New York, United States
Montefiore Med Ctr Adolescent Aids Program
The Bronx, New York, United States
Duke Univ Med Ctr
Durham, North Carolina, United States
Columbus Children'S Hosp
Columbus, Ohio, United States
Med Univ of South Carolina
Charleston, South Carolina, United States
Saint Jude Children'S Research Hosp of Memphis
Memphis, Tennessee, United States
Children'S Med Ctr of Dallas
Dallas, Texas, United States
Texas Children'S Hosp / Baylor Univ
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Abacavir →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: —
Primary completion: —
Completion: 31 Aug 2002
Last update posted: 1 Nov 2021
Registered enrollment: 24
Registry id: NCT00011479

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.