Clinical trialNCT00013871CompletedInterventional

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment300HIV InfectionsHepatitis BMeaslesPertussisPneumococcal Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine if 2 doses of Pneumococcal Conjugate Vaccine (PCV) followed by 1 dose of Pneumococcal Polysaccharide Vaccine (PPV) in HIV-infected children on anti-HIV therapy is helpful and safe in fighting pneumococcal infections in this group of children. This study will also look at the protection provided by childhood vaccination against measles, pertussis, and hepatitis B virus. Pneumococcal infections are the most common AIDS-related infection in HIV-infected children. PCV may help reduce the chances of HIV-infected children getting pneumococcal infections. This study will look at whether pneumococcal vaccines are safe and effective in HIV-infected children receiving HAART. It will look at whether HIV-infected children are protected by childhood vaccines received previously and if more doses are safe and improve protection.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Mark Abzug
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

40 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

San Juan City Hosp. Pr Nichd Crs
San Juan, Puerto Rico
Univ. of Puerto Rico Ped. Hiv/aids Research Program Crs
San Juan, Puerto Rico

United States

Uab, Dept. of Ped., Div. of Infectious Diseases
Birmingham, Alabama, United States
Long Beach Memorial Med. Ctr., Miller Children'S Hosp.
Long Beach, California, United States
Usc la Nichd Crs
Los Angeles, California, United States
Children'S Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab.
Oakland, California, United States
Ucsd Mother-Child-Adolescent Program Crs
San Diego, California, United States
Ucsf Pediatric Aids Crs
San Francisco, California, United States
Univ. of Colorado Denver Nichd Crs
Aurora, Colorado, United States
Connecticut Children'S Med. Ctr.
Hartford, Connecticut, United States
Yale Univ. School of Medicine - Dept. of Peds., Div. of Infectious Disease
New Haven, Connecticut, United States
Children'S National Med. Ctr. Washington Dc Nichd Crs
Washington D.C., District of Columbia, United States
South Florida Cdtc Ft Lauderdale Nichd Crs
Fort Lauderdale, Florida, United States
Univ. of Florida College of Medicine-Dept of Peds, Div. of Immunology, Infectious Diseases & Allergy
Gainesville, Florida, United States
Univ. of Florida Jacksonville Nichd Crs
Jacksonville, Florida, United States
Univ. of Miami Ped. Perinatal Hiv/aids Crs
Miami, Florida, United States
Columbus Regional Healthcare System, the Med. Ctr.
Columbus, Georgia, United States
Chicago Children'S Crs
Chicago, Illinois, United States
Univ. of Chicago - Dept. of Peds., Div. of Infectious Disease
Chicago, Illinois, United States
Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases
Baltimore, Maryland, United States
Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology
Baltimore, Maryland, United States
Bmc, Div. of Ped Infectious Diseases
Boston, Massachusetts, United States
Hms - Children'S Hosp. Boston, Div. of Infectious Diseases
Boston, Massachusetts, United States
Baystate Health, Baystate Med. Ctr.
Springfield, Massachusetts, United States
Wne Maternal Pediatric Adolescent Aids Crs
Worcester, Massachusetts, United States
Rutgers - New Jersey Medical School Crs
Newark, New Jersey, United States
Suny Downstate Med. Ctr., Children'S Hosp. at Downstate Nichd Crs
Brooklyn, New York, United States
Schneider Children'S Hosp., Div. of Infectious Diseases
New Hyde Park, New York, United States
Columbia Impaact Crs
New York, New York, United States
Cornell Univ., Div. of Ped. Infectious Diseases & Immunology
New York, New York, United States
Harlem Hosp. Ctr. Ny Nichd Crs
New York, New York, United States
Metropolitan Hosp. Ctr.
New York, New York, United States
Nyu Ny Nichd Crs
New York, New York, United States
St. Luke'S-Roosevelt Hosp. Ctr.
New York, New York, United States
Strong Memorial Hospital Rochester Ny Nichd Crs
Rochester, New York, United States
Suny Stony Brook Nichd Crs
Stony Brook, New York, United States
Bronx-Lebanon Hosp. Impaact Crs
The Bronx, New York, United States
Montefiore Med. Ctr. - Aecom
The Bronx, New York, United States
St. Christopher'S Hosp. for Children
Philadelphia, Pennsylvania, United States
Texas Children'S Hosp. Crs
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine AdsorbedHEPATITIS B VACCINE (RECOMBINANT)Measles-Mumps-Rubella VaccinePneumococcal Conjugate Vaccine, HeptavalentPNEUMOCOCCAL VACCINE

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: —
Primary completion: —
Completion: 30 Nov 2004
Last update posted: 1 Nov 2021
Registered enrollment: 300
Registry id: NCT00013871

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Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.