Clinical trialNCT00024518CompletedPhase 2Interventional

Interferon-Alpha for Diabetes Mellitus Type 1

SponsorThe University of Texas Health Science Center, HoustonEnrollment57Insulin-Dependent Diabetes Mellitus

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will see if interferon-alpha given early in the disease can stop or slow the immune attack on insulin-producing cells. In addition, the study will examine the safety and efficacy of interferon-alpha (given by mouth) to protect beta cell function. Patients between 3 and 25 years of age with Type 1 Diabetes Mellitus less then six weeks may be eligible for this study. All study-related tests and medications at the NIH Clinical Center are provided at no cost.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Kristina I Rother, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Principal Investigator
clinicaltrials.gov ↗
Staley A Brod, MD
The University of Texas Health Science Center, Houston
Principal InvestigatorKOL profile →
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
Children'S Hospital - St. Paul
Saint Paul, Minnesota, United States
Children'S Hospital - Kansas City
Kansas City, Missouri, United States
University of Texas, Dallas
Dallas, Texas, United States
University of Texas, Houston
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

30,000 units hrINF-alpha5,000 hrINF-alpha

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Sept 2001
Primary completion: 30 Sept 2008
Completion: 30 Sept 2008
Last update posted: 19 Nov 2013
Registered enrollment: 57
Registry id: NCT00024518

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.