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Clinical trialNCT00027040CompletedInterventional

A Study of Decreased Mental Function Associated With HIV

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment90Cognitive DisordersHIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare pictures of the brain of HIV-infected people with memory problems before and after treatment with selegiline. Selegiline is the study drug received through A5090. HIV patients generally develop memory problems late in the disease. This will be examined using noninvasive proton magnetic resonance spectroscopy (1H-MRS). The effect of the drug selegiline on memory problems also will be examined.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Ucla Care Ctr

    Los Angeles, California, United States

  • Univ of California, San Diego

    San Diego, California, United States

  • Stanford University

    Stanford, California, United States

  • Johns Hopkins Hosp

    Baltimore, Maryland, United States

  • Columbia Presbyterian Med Ctr

    New York, New York, United States

  • Mount Sinai Med Ctr

    New York, New York, United States

  • Univ of Rochester Medical Center

    Rochester, New York, United States

  • Univ of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Rhode Island Hosp

    Providence, Rhode Island, United States

  • Stanley Street Treatment and Resource

    Providence, Rhode Island, United States

  • the Miriam Hosp

    Providence, Rhode Island, United States

  • Univ of Washington

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Selegiline →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
—
Primary completion
—
Completion
30 Jun 2005
Last update posted
16 Jan 2015
Registered enrollment
90
Registry id
NCT00027040
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.