Clinical trialNCT00028145CompletedObservational

Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission

SponsorInternational Maternal Pediatric Adolescent AIDS Clinical Trials GroupEnrollment3,090HIV InfectionsPregnancy Complications, Infectious

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to collect and study clinical and laboratory information about a pregnant or new mother and her medical care that will increase our knowledge of the best care for HIV-infected pregnant women and their children. The rate of transmission of HIV from mothers to their infants has gone down. Specific U.S. Public Health Service guidelines recommend that HIV-infected pregnant women be treated with anti-HIV therapies; but the effectiveness of treatment and safety for the mother and her infant have not been fully examined. This study will monitor the health of women and their infants while they receive anti-HIV therapy. Also, this study will provide information that may be used for future studies.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Gwen Scott, MD
Pediatric Infectious Diseases, University of Miami School of Medicine
Study Chair
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Ruth Tuomala, MD
Director of Obstetrics and Gynecology, Brigham and Women's Hospital
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

77 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

San Juan City Hosp. Pr Nichd Crs (5031)
San Juan, Puerto Rico
University of Puerto Rico Pediatric Hiv/aids (6601)
San Juan, Puerto Rico

United States

Univ. of Alabama Birmingham Nichd Crs (5096)
Birmingham, Alabama, United States
University of South Alabama
Mobile, Alabama, United States
Phoenix Childrens Hospital
Phoenix, Arizona, United States
Long Beach Memorial (pediatric)
Long Beach, California, United States
Miller Children'S Hospital Long Beach (5093)
Long Beach, California, United States
Los Angeles County Medical Center/usc
Los Angeles, California, United States
Ucla Med Ctr / Pediatric
Los Angeles, California, United States
Ucla-Los Angeles/brazil Aids Consortium (labac) Cr (3601)
Los Angeles, California, United States
Usc la Nichd Crs (5048)
Los Angeles, California, United States
Univ of California, San Diego (4601)
San Diego, California, United States
Univ. of California San Francisco Nichd Crs (5091)
San Francisco, California, United States
Harbor-Ucla Med Ctr (5045)
Torrance, California, United States
University of Colorado Denver Nichd Crs (5052)
Denver, Colorado, United States
Connecticut Childrens Medical Center (pediatric)
Farmington, Connecticut, United States
University of Connecticut, Farmington
Farmington, Connecticut, United States
Yale Univ School of Med
New Haven, Connecticut, United States
Children'S National Medical Center Washington Dc Nichd Crs (5015)
Washington D.C., District of Columbia, United States
Howard Univ Hosp (5044)
Washington D.C., District of Columbia, United States
Washington Hospital Center Nichd Crs (5023)
Washington D.C., District of Columbia, United States
South Florida Cdc Ft Lauderdale Nichd Crs (5055)
Fort Lauderdal, Florida, United States
North Broward Hosp District
Fort Lauderdale, Florida, United States
University of Florida Jacksonville (5051)
Jacksonville, Florida, United States
Jackson Memorial Hosp
Miami, Florida, United States
University of Miami Pediatric/perinatal Hiv/aids (4201)
Miami, Florida, United States
University of South Florida at Tampa (5018)
St. Petersburg, Florida, United States
Med College of Georgia
Augusta, Georgia, United States
the Medical Center
Columbus, Georgia, United States
Chicago Childrens Memorial Hosp (pediatric)
Chicago, Illinois, United States
Cook County Hospital
Chicago, Illinois, United States
Mt Sinai Hosp Med Ctr / Dept of Pediatrics
Chicago, Illinois, United States
Rush University Cook County Hospital Nichd Crs (5083)
Chicago, Illinois, United States
Univ of Chicago Children'S Hosp (4001)
Chicago, Illinois, United States
Univ of Illinois
Chicago, Illinois, United States
Womens & Childrens Hiv Program
Chicago, Illinois, United States
Tulane University Charity Hosp of New Orleans (7201)
New Orleans, Louisiana, United States
Tulane University New Orleans (5095)
New Orleans, Louisiana, United States
Tulane-Lakeside Hospital
New Orleans, Louisiana, United States
Johns Hopkins University Nichd Crs (5092)
Baltimore, Maryland, United States

37 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2002
Primary completion: 30 Jun 2013
Completion: 30 Jun 2013
Last update posted: 10 Oct 2014
Registered enrollment: 3,090
Registry id: NCT00028145

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.