Clinical trialNCT00043849CompletedPhase 4Interventional

Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)

SponsorNational Institute on Aging (NIA)Enrollment60DementiaParkinson Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary aim of this study is to determine the safety and efficacy of quetiapine (Seroquel) for the treatment of psychosis and/or agitation in patients with primary dementia complicated by coexistent parkinsonism, or patients with Parkinson's disease with dementia \[PDD\] who have episodes of agitation or psychosis. The secondary aim is to determine the safety and tolerability, particularly the influence on parkinsonism, of quetiapine when used to treat psychosis and/or agitation in patients with dementia complicated by coexistent parkinsonism.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Roger Kurlan, MD
University of Rochester Medical Center, Department of Neurology
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

21 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham, Alzheimer'S Disease Research Center
Birmingham, Alabama, United States
University of California, San Diego, Alzheimer'S Disease Center
La Jolla, California, United States
Va Healthcare System Long Beach
Long Beach, California, United States
University of California at Los Angeles, Alzheimer'S Disease Center
Los Angeles, California, United States
Stanford/va Aging Clinical Research Center, Department of Psychiatry & Behavioral Sciences
Palo Alto, California, United States
Emory University, Alzheimer'S Disease Center
Atlanta, Georgia, United States
Medical College of Georgia
Augusta, Georgia, United States
Rush University Medical Center
Chicago, Illinois, United States
Southern Illinois University, School of Medicine
Springfield, Illinois, United States
E. N. Rogers Memorial Veterans Hospital
Bedford, Massachusetts, United States
University of Nevada
Las Vegas, Nevada, United States
Parkinson'S Disease and Movement Disorders Center, Albany Medical College
Albany, New York, United States
Maimonides Medical Center
Brooklyn, New York, United States
Columbia University, Alzheimer'S Disease Research Center
New York, New York, United States
University of Rochester Medical Center, Alzheimer'S Disease Center
Rochester, New York, United States
Syracuse Va Medical Center
Syracuse, New York, United States
University of Pittsburgh, Alzheimer'S Disease Research Center
Pittsburgh, Pennsylvania, United States
University of Texas Southwestern Medical Center at Dallas, Alzheimer'S Disease Center
Dallas, Texas, United States
Memory Clinic at Southwestern Vermont Medical Center
Bennington, Vermont, United States
Fletcher Allan Health Care, Inc.
Burlington, Vermont, United States
University of Washington at Seattle, Alzheimer'S Disease Research Center
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Quetiapine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2002
Primary completion: 30 Jun 2005
Completion: 30 Jun 2005
Last update posted: 11 Dec 2009
Registered enrollment: 60
Registry id: NCT00043849

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.