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Clinical trialNCT00050271CompletedInterventional

Acetyl-L-Carnitine for the Treatment of NRTI-Associated Peripheral Neuropathy

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment27HIV InfectionsPeripheral Nervous System Diseases
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine if acetyl-L-carnitine (ALC) reduces pain, numbness, and tingling in the feet and legs of patients with nucleoside reverse transcriptase inhibitor (NRTI)-associated peripheral neuropathy. Another purpose is to determine if ALC is safe and tolerable in HIV patients who have taken certain anti-HIV drugs.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico
  • Puerto Rico-Aids Crs

    San Juan, Puerto Rico

United States
  • Stanford Crs

    Palo Alto, California, United States

  • the Ponce de Leon Ctr. Crs

    Atlanta, Georgia, United States

  • Univ. of Hawaii at Manoa, Leahi Hosp.

    Honolulu, Hawaii, United States

  • Cook County Hosp. Core Ctr.

    Chicago, Illinois, United States

  • Northwestern University Crs

    Chicago, Illinois, United States

  • Johns Hopkins Adult Aids Crs

    Baltimore, Maryland, United States

  • Washington U Crs

    St Louis, Missouri, United States

  • Beth Israel Med. Ctr., Actu

    New York, New York, United States

  • Weill Med. College of Cornell Univ., the Cornell Ctu

    New York, New York, United States

  • University of Washington Aids Crs

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Acetylcarnitine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
—
Primary completion
—
Completion
31 Jan 2007
Last update posted
1 Nov 2021
Registered enrollment
27
Registry id
NCT00050271
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.