Clinical trialNCT00056563CompletedPhase 3Interventional

Phase I Deep Brain Stimulation (DBS) vs. Best Medical Therapy (BMT) Trial

SponsorUS Department of Veterans AffairsEnrollment255Parkinson's Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goals of this study are to determine if simultaneous bilateral subthalamic nucleus stimulation or simultaneous bilateral globus pallidus stimulation is more effective in reducing symptoms of Parkinson's disease, and if deep brain stimulation or best medical therapy is more effective in improving Parkinson's disease symptoms

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Frances M. Weaver, PhD MA BA
Edward Hines Jr. VA Hospital
Study Chair
clinicaltrials.gov ↗
Kenneth Follett
VA Medical Center, Iowa City
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California at Los Angeles
Los Angeles, California, United States
University of California at San Francisco
San Francisco, California, United States
Va Medical Center, San Francisco
San Francisco, California, United States
Va Greater Los Angeles Healthcare System, West la
West Los Angeles, California, United States
Va Medical Center, Iowa City
Iowa City, Iowa, United States
Oregon Health Sciences University
Portland, Oregon, United States
Va Medical Center, Portland
Portland, Oregon, United States
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States
Va Medical Center, Philadelphia
Philadelphia, Pennsylvania, United States
Baylor College of Medicine
Houston, Texas, United States
Michael E. Debakey Va Medical Center (152)
Houston, Texas, United States
Hunter Holmes Mcguire Va Medical Center
Richmond, Virginia, United States
Medical College of Virginia
Richmond, Virginia, United States
Va Puget Sound Health Care System, Seattle
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Apr 2002
Primary completion: 31 Oct 2008
Completion: 31 Oct 2008
Last update posted: 9 May 2014
Registered enrollment: 255
Registry id: NCT00056563

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.