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Clinical trialNCT00069953CompletedPhase 2Interventional

Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

SponsorRadiation Therapy Oncology GroupEnrollment43Esophageal Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy such as paclitaxel, fluorouracil, and cisplatin use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells PURPOSE: This phase II trial is studying how well combination chemotherapy followed by chemoradiotherapy, with or without surgery, works in treating patients with resectable locally advanced cancer of the esophagus or gastroesophageal junction.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

97 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Providence Saint Joseph Medical Center - Burbank

    Burbank, California, United States

  • Saint Rose Hospital

    Hayward, California, United States

  • Providence Holy Cross Cancer Center

    Mission Hills, California, United States

  • Ccop - Bay Area Tumor Institute

    Oakland, California, United States

  • Summit Medical Center

    Oakland, California, United States

  • Valley Care Medical Center

    Pleasanton, California, United States

  • J.C. Robinson, M.D. Regional Cancer Center

    San Pablo, California, United States

  • University of Colorado Cancer Center at University of Colorado Health Sciences Center

    Aurora, Colorado, United States

  • Hospital of Saint Raphael

    New Haven, Connecticut, United States

  • Baptist-South Miami Regional Cancer Program

    Miami, Florida, United States

  • Gulf Coast Cancer Treatment Center

    Panama City, Florida, United States

  • Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

    Savannah, Georgia, United States

  • Mount Sinai Hospital Medical Center

    Chicago, Illinois, United States

  • St. Francis Hospital and Health Centers - Beech Grove Campus

    Beech Grove, Indiana, United States

  • Wendt Regional Cancer Center at Finley Hospital

    Dubuque, Iowa, United States

  • Ochsner Clinic of Baton Rouge

    Baton Rouge, Louisiana, United States

  • Ccop - Ochsner

    New Orleans, Louisiana, United States

  • Ccop - Michigan Cancer Research Consortium

    Ann Arbor, Michigan, United States

  • St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital

    Ann Arbor, Michigan, United States

  • Oakwood Cancer Center at Oakwood Hospital and Medical Center

    Dearborn, Michigan, United States

  • Green Bay Oncology, Limited - Escanaba

    Escanaba, Michigan, United States

  • Genesys Hurley Cancer Institute

    Flint, Michigan, United States

  • Van Elslander Cancer Center at St. John Hospital and Medical Center

    Grosse Pointe Woods, Michigan, United States

  • Green Bay Oncology, Limited - Iron Mountain

    Iron Mountain, Michigan, United States

  • Foote Hospital

    Jackson, Michigan, United States

  • Sparrow Regional Cancer Center

    Lansing, Michigan, United States

  • Seton Cancer Institute - Saginaw

    Saginaw, Michigan, United States

  • St. John Macomb Hospital

    Warren, Michigan, United States

  • Fairview Ridges Hospital

    Burnsville, Minnesota, United States

  • Mercy and Unity Cancer Center at Mercy Hospital

    Coon Rapids, Minnesota, United States

  • Fairview Southdale Hospital

    Edina, Minnesota, United States

  • Mercy and Unity Cancer Center at Unity Hospital

    Fridley, Minnesota, United States

  • Virginia Piper Cancer Institute at Abbott-Northwestern Hospital

    Minneapolis, Minnesota, United States

  • Hubert H. Humphrey Cancer Center at North Memorial Medical Center

    Robbinsdale, Minnesota, United States

  • Ccop - Metro-Minnesota

    Saint Louis Park, Minnesota, United States

  • Park Nicollet Health Services

    Saint Louis Park, Minnesota, United States

  • United Hospital

    Saint Paul, Minnesota, United States

  • Ridgeview Medical Center

    Waconia, Minnesota, United States

  • Hattiesburg Clinic, P.A.

    Hattiesburg, Mississippi, United States

  • Ccop - Cancer Research for the Ozarks

    Springfield, Missouri, United States

57 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Sept 2003
Primary completion
31 Mar 2007
Completion
31 Dec 2016
Last update posted
17 Feb 2017
Registered enrollment
43
Registry id
NCT00069953

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.