Clinical trialNCT00070434WithdrawnPhase 2Interventional

S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum

SponsorSWOG Cancer Research NetworkEnrollment0Colorectal Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy, such as irinotecan, leucovorin, fluorouracil, and oxaliplatin, use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well different regimens of induction chemotherapy followed by chemoradiotherapy work in treating patients with locally advanced adenocarcinoma of the rectum.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Charles R. Thomas, MD
The University of Texas Health Science Center at San Antonio
Study Chair
clinicaltrials.gov ↗
Heinz-Josef Lenz, MD
University of Southern California
Study ChairKOL profile →
clinicaltrials.gov ↗
James L. Abbruzzese, MD
M.D. Anderson Cancer Center
Study Chair
clinicaltrials.gov ↗
Morton S. Kahlenberg, MD
The University of Texas Health Science Center at San Antonio
Study Chair
clinicaltrials.gov ↗
Robert P. Whitehead, MD
University of Texas
Study Chair
clinicaltrials.gov ↗
Stephen R. Smalley, MD
Radiation Oncology Center of Olathe
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PyridoxineCapecitabine →Fluorouracil →Irinotecan →Leucovorin →Oxaliplatin →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2004
Primary completion: 28 Feb 2006
Completion: —
Last update posted: 7 Jun 2012
Registered enrollment: 0
Registry id: NCT00070434

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.