Clinical trialNCT00070473CompletedPhase 1Interventional

Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors

SponsorChildren's Oncology GroupEnrollment33Unspecified Childhood Solid Tumor, Protocol Specific

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, use different ways to stop tumor cells from dividing so they stop growing or die. Pemetrexed disodium may stop the growth of tumor cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of pemetrexed disodium in treating young patients with recurrent solid tumors.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

H. Stacy Nicholson, MD, MPH
OHSU Knight Cancer Institute
Study Chair
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Linda C. Stork, MD
Doernbecher Children's Hospital at Oregon Health and Science University
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Hospital for Sick Children
Toronto, Ontario, Canada
Hopital Sainte Justine
Montreal, Quebec, Canada

United States

Children'S Hospital Los Angeles
Los Angeles, California, United States
Stanford Cancer Center at Stanford University Medical Center
Stanford, California, United States
Children'S National Medical Center
Washington D.C., District of Columbia, United States
Indiana University Cancer Center
Indianapolis, Indiana, United States
Nci - Pediatric Oncology Branch
Bethesda, Maryland, United States
Dana-Farber/harvard Cancer Center at Dana Farber Cancer Institute
Boston, Massachusetts, United States
Fairview University Medical Center - University Campus
Minneapolis, Minnesota, United States
Mayo Clinic Cancer Center
Rochester, Minnesota, United States
University of Mississippi Medical Center
Jackson, Mississippi, United States
Herbert Irving Comprehensive Cancer Center at Columbia University
New York, New York, United States
Suny Upstate Medical University Hospital
Syracuse, New York, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Cancer Institute at Oregon Health and Science University
Portland, Oregon, United States
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Children'S Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
Dallas, Texas, United States
Baylor University Medical Center - Houston
Houston, Texas, United States
Children'S Hospital and Regional Medical Center - Seattle
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Pemetrexed →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2003
Primary completion: 31 Mar 2006
Completion: 30 Jun 2008
Last update posted: 20 Feb 2014
Registered enrollment: 33
Registry id: NCT00070473

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.