Clinical trialNCT00075907CompletedPhase 3Interventional

Anti-HIV Drug Regimens With or Without Protease Inhibitors and Drug Level Monitoring in HIV Infected Adolescents

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment240HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare the effectiveness of anti-HIV drug regimens with or without a protease inhibitor (PI) in HIV infected adolescents. It will also determine if monitoring drug levels and adjusting the dose as necessary improves the effectiveness of these regimens.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Margarita Silio, MD
Tulane Medical Center
Study Chair
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Russell Van Dyke, MD
Tulane Medical Center
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Usc la Nichd Crs
Alhambra, California, United States
Long Beach Memorial Med. Ctr., Miller Children'S Hosp.
Long Beach, California, United States
Children'S Hospital of Los Angeles Nichd Crs
Los Angeles, California, United States
Univ. of Colorado Denver Nichd Crs
Aurora, Colorado, United States
Chicago Children'S Crs
Chicago, Illinois, United States
Children'S Hosp.
New Orleans, Louisiana, United States
Tulane/lsu Maternal/child Crs
New Orleans, Louisiana, United States
Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases
Baltimore, Maryland, United States
Suny Stony Brook Nichd Crs
Stony Brook, New York, United States
Bronx-Lebanon Hosp. Impaact Crs
The Bronx, New York, United States
St. Jude/uthsc Crs
Memphis, Tennessee, United States
Children'S Med. Ctr. Dallas
Dallas, Texas, United States
Texas Children'S Hosp. Crs
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Efavirenz + 2 NRTIsLopinavir →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2004
Primary completion: —
Completion: 30 Sept 2006
Last update posted: 7 Oct 2013
Registered enrollment: 240
Registry id: NCT00075907

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.