Clinical trialNCT00078845CompletedPhase 2Interventional

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors

SponsorM.D. Anderson Cancer CenterEnrollment24Breast CancerLung CancerNeurotoxicityOvarian CancerProstate CancerUnspecified Adult Solid Tumor, Protocol Specific

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Amifostine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. PURPOSE: This phase II trial is studying how well amifostine works in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy in patients who have received paclitaxel for solid tumors.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Arthur Forman, MD
M.D. Anderson Cancer Center
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Ccop - Central Illinois
Decatur, Illinois, United States
Ccop - Carle Cancer Center
Urbana, Illinois, United States
Ccop - Wichita
Wichita, Kansas, United States
Christus St. Frances Cabrini Center for Cancer Care
Alexandria, Louisiana, United States
Ccop - Grand Rapids
Grand Rapids, Michigan, United States
Ccop - Kalamazoo
Kalamazoo, Michigan, United States
Ccop - Kansas City
Kansas City, Missouri, United States
Cancer Research for the Ozarks
Springfield, Missouri, United States
Ccop - Columbus
Columbus, Ohio, United States
Ccop - Upstate Carolina
Spartanburg, South Carolina, United States
University of Texas M.D. Anderson Ccop Research Base
Houston, Texas, United States
Ccop - Scott and White Hospital
Temple, Texas, United States
Ccop - Northwest
Tacoma, Washington, United States
Ccop - Marshfield Clinic Research Foundation
Marshfield, Wisconsin, United States
All Saints Cancer Center at Wheaton Franciscan Healthcare
Racine, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Amifostine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2004
Primary completion: 31 May 2007
Completion: 31 May 2007
Last update posted: 17 Oct 2012
Registered enrollment: 24
Registry id: NCT00078845

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.