findmyKOL
Clinical trialNCT00086359CompletedPhase 3Interventional

Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment19HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Pregnant women infected with HIV who take anti-HIV medications during pregnancy lower the risk of passing HIV to their infants. This study will compare how well two different combinations of anti-HIV medications control HIV in pregnancy, and whether these combinations of drugs are effective in preventing HIV from being transmitted from a pregnant woman to her baby. The two combinations are abacavir/lamivudine/zidovudine (ABC/3TC/ZDV) and zidovudine/lamivudine (ZDV/3TC) plus lopinavir/ritonavir (LPV/RTV).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Andrew D. Hull, MD

    Department of Reproductive Medicine, Division of Perinatal Medicine, University of California, San Diego School of Medicine

    Study Chair
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico
  • San Juan City Hosp. Pr Nichd Crs

    San Juan, Puerto Rico

United States
  • Usc la Nichd Crs

    Los Angeles, California, United States

  • Ucsd Mother-Child-Adolescent Program Crs

    San Diego, California, United States

  • Univ. of Miami Ped. Perinatal Hiv/aids Crs

    Miami, Florida, United States

  • Mt. Sinai Hosp. Med. Ctr. - Chicago, Womens & Childrens Hiv Program

    Chicago, Illinois, United States

  • Bronx-Lebanon Crs

    The Bronx, New York, United States

  • Regional Med. Ctr. at Memphis

    Memphis, Tennessee, United States

  • Texas Children'S Hosp. Crs

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Abacavir →Lamivudine →Lopinavir →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jul 2004
Primary completion
—
Completion
30 Sept 2007
Last update posted
1 Nov 2021
Registered enrollment
19
Registry id
NCT00086359
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.