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Clinical trialNCT00091949CompletedPhase 3Interventional

Insulin Resistance Intervention After Stroke Trial

SponsorYale UniversityEnrollment3,876DiabetesMyocardial InfarctionStroke
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine if pioglitazone is effective in preventing future strokes or heart attacks among non-diabetic persons who have had a recent ischemic stroke.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

183 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Flinders Medical Centre

    Bedford Park, New South Wales, Australia

  • Royal Prince Alfred

    Camperstown, New South Wales, Australia

  • John Hunter Hospital (university of Newcastle)

    New Lambton Heights, New South Wales, Australia

  • Box Hill Hospital (eastern Health)

    Box Hill, Victoria, Australia

  • Western Hospital (university of Melbourne)

    Footscray, Victoria, Australia

  • Austin Health (national Stroke Research Institute)

    Heidelberg Heights, Victoria, Australia

  • Royal Melbourne Hospital

    Parkville, Victoria, Australia

  • Royal Perth

    Perth, Western Australia, Australia

Canada
  • University of Alberta

    Edmonton, Alberta, Canada

  • Center for Neurologic Research

    Lethbridge, Alberta, Canada

  • Vancouver Island Health Research Centre

    Victoria, British Columbia, Canada

  • Robarts Research Institute

    London, Ontario, Canada

  • Ottawa Hospital-General Campus

    Ottawa, Ontario, Canada

  • Intermountain Research Consultants

    Thunder Bay, Ontario, Canada

  • St. Michael'S Hospital

    Toronto, Ontario, Canada

  • Hôpital Charles Lemoyne

    Greenfield Park, Quebec, Canada

  • Mcgill-Jewish General

    Montreal, Quebec, Canada

  • Mcgill-Montreal General

    Montreal, Quebec, Canada

  • Centre Hospitalier Affilie Universitaire de Quebec

    Québec, Quebec, Canada

  • Chum-Centre de Recherche, Hôpital Notre-Dame

    Montreal, Canada

Germany
  • Klinikum Altenburger Land

    Altenburg, Germany

  • Neurologische Klinik

    Bad Neustadt an der Saale, Germany

  • University Hospital-Dresden

    Dresden, Germany

  • University Duesseldorf/heinrich-Heine University

    Düsseldorf, Germany

  • University of Erlangen

    Erlangen, Germany

  • Alfried Krupp Hospital

    Essen, Germany

  • University Hospital Frankfurt

    Frankfurt, Germany

  • Freiburg University

    Freiburg im Breisgau, Germany

  • Ernst-Moritz-Arndt-University Greifswald

    Greifswald, Germany

  • Martin-Luther-Universitaet Halle-Wittenberg

    Halle, Germany

  • University Medical Center Hamburg-Eppendorf

    Hamburg, Germany

  • University Heidelberg

    Heidelberg, Germany

  • Friedrich Schiller-University Jena

    Jena, Germany

  • University Hospital Mainz

    Mainz, Germany

  • Klinikum Der Universitat Muenchen

    Munich, Germany

  • University Hospital Muenster

    Münster, Germany

  • University of Ulm

    Ulm, Germany

Israel
  • Soroka Medical Center

    Beersheba, Israel

  • B'Nai Zion Medical Center

    Haifa, Israel

  • Bnai-Zion Medical Center

    Haifa, Israel

143 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PioglitazonePlacebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
28 Feb 2005
Primary completion
30 Nov 2015
Completion
30 Nov 2015
Last update posted
27 Apr 2020
Registered enrollment
3,876
Registry id
NCT00091949

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.