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Clinical trialNCT00100867CompletedObservational

Effects of Maternal Anti-HIV Treatment on Infants Born to HIV-Infected Women

SponsorAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsEnrollment236HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

In clinical trials being conducted throughout the world, pregnant HIV-infected women are given anti-HIV drugs before, during, and after they give birth to prevent mother-to-child transmission of HIV. However, the effects of this anti-HIV treatment on infants is unknown. The purpose of this study is to determine the safety, toxicity, and potential side effects of maternal anti-HIV treatment on infants born to these HIV-infected women. Study hypothesis: Specific combination antiretroviral regimens used in clinical trials in diverse areas of the world are safe and well tolerated during pregnancy and breastfeeding periods, and are not associated with adverse side effects to the fetus, neonate, and/or breastfeeding infant. These regimens are associated with reduction of mother-to-child HIV transmission.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

23 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Botswana
  • the Gaborone Bhp Study Clinic

    Gaborone, Botswana

  • the Molepolole Bhp Study Clinic

    Gaborone, Botswana

Brazil
  • Hospital Geral de Nova Iguacu

    Rio de Janeiro, Brazil

  • Hospital Dos Servidores Do Estado

    Rio de Janeiro, Brazil

  • Instituto de Pesquisa Clinica Evandro Chagas Fiocruz, Fundacao Oswaldo Cruz

    Rio de Janeiro, Brazil

India
  • Yrg Center for Aids Research and Education

    Chennai, India

  • Nari Aids Research Institute, Department of Clinical Science

    Pune, India

  • Nari Aids Research Institute, Dr. Kotnis Dispensary

    Pune, India

  • Nari-Niv Clinic

    Pune, India

Malawi
  • Univ. of Malawi, John Hopkins Project

    Blantyre, Malawi

  • University of North Carolina Project (unc Project)

    Lilongwe, Malawi

Peru
  • Asociacion Civil Impacta Salud Y Educacion,

    Miraflores, Lima region, Peru

  • Asociacion Civil Impacta Salud Y Educacion, Lince

    Lima, Peru

South Africa
  • Perinatal Hiv Research Unit at Chris Baragwanath Hospital

    Johannesburg, South Africa

  • University of the Witwatersrand

    Johannesburg, South Africa

Thailand
  • Siriraj Hospital

    Bangkok Noi, Bankok, Thailand

  • Chonburi Regional Hospital, Chonburi

    Muang, Changwat Chon Buri, Thailand

  • Phayao Provincial Hospital, Phayao

    Tambol Mae Sai, Muang Phayao, Thailand

  • Bhumibol Adulyadej Hospital, Bangkok

    Bangkok, Thailand

  • Chiang Mai University

    Chang Mai, Thailand

  • Institut de Recherche Pour Developpement (ird)

    Chiang Mai, Thailand

  • Prapokklao Hospital Chantaburi

    Muang Chantaburi, Thailand

Zimbabwe
  • University of Zimbabwe

    Harare, Zimbabwe

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2006
Primary completion
31 May 2010
Completion
31 May 2010
Last update posted
1 Apr 2016
Registered enrollment
236
Registry id
NCT00100867
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.