Clinical trialNCT00245284CompletedObservational

Predictor of Advanced Subclinical Atherosclerosis

SponsorPreMDEnrollment600Coronary Artery Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Evaluation of skin cholesterol for cardiovascular risk assessment in asymptomatic individuals at low, intermediate, or high risk based on Framingham Global Risk estimates. Carotid intima-media thickness (IMT), a surrogate marker for atherosclerotic burden, that independently predicts the occurrence of heart attack and stroke, will be the "gold standard" comparator. Hypothesis: Skin cholesterol, as measured by two non-invasive tests, correlates with CAD, as measured by CIMT in this population.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Decara Jeanne, MD
University of Chicago
Principal Investigator
clinicaltrials.gov ↗
Hirsch Alan, MD
University of Minnesota
Principal Investigator
clinicaltrials.gov ↗
James Stein, MD
University of Wisconsin, Madison
Principal Investigator
clinicaltrials.gov ↗
Michael Davidson, MD
Radiant Research - Chicago
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Mohler Emile, MD
University of Pennsylvania
Principal Investigator
clinicaltrials.gov ↗
Ouyang Pamela, MD
Johns Hopkins University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Radiant Research
Chicago, Illinois, United States
University of Chicago
Chicago, Illinois, United States
Johns Hopkins Hospital
Baltimore, Maryland, United States
University of Minnesota
Minneapolis, Minnesota, United States
University Od Pennsylvania
Philadelphia, Pennsylvania, United States
University of Wisconsin
Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Sept 2005
Primary completion: —
Completion: 31 May 2006
Last update posted: 6 Jun 2006
Registered enrollment: 600
Registry id: NCT00245284

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.