Clinical trialNCT00257127CompletedInterventional

Immune System Function Following Vaccination in HIV Infected Children Taking Anti-HIV Drugs

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment101HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine immune system function following vaccination in HIV-infected children currently taking anti-HIV drugs. To test the effectiveness of prior vaccination, patients in this study will receive booster shots of one of two pneumococcal vaccines, a hepatitis B vaccine, and a measles vaccine.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Mark Abzug, MD
The Children's Hospital, Denver, CO
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

26 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

San Juan City Hosp. Pr Nichd Crs
San Juan, Puerto Rico
Univ. of Puerto Rico Ped. Hiv/aids Research Program Crs
San Juan, Puerto Rico

United States

Uab, Dept. of Ped., Div. of Infectious Diseases
Birmingham, Alabama, United States
Usc la Nichd Crs
Alhambra, California, United States
Long Beach Memorial Med. Ctr., Miller Children'S Hosp.
Long Beach, California, United States
Ucsd Mother-Child-Adolescent Program Crs
San Diego, California, United States
Univ. of Colorado Denver Nichd Crs
Aurora, Colorado, United States
Yale Univ. School of Medicine - Dept. of Peds., Div. of Infectious Disease
New Haven, Connecticut, United States
South Florida Cdtc Ft Lauderdale Nichd Crs
Fort Lauderdale, Florida, United States
Univ. of Florida College of Medicine-Dept of Peds, Div. of Immunology, Infectious Diseases & Allergy
Gainesville, Florida, United States
Univ. of Florida Jacksonville Nichd Crs
Jacksonville, Florida, United States
Chicago Children'S Crs
Chicago, Illinois, United States
Univ. of Chicago - Dept. of Peds., Div. of Infectious Disease
Chicago, Illinois, United States
Children'S Hosp.
New Orleans, Louisiana, United States
Bmc, Div. of Ped Infectious Diseases
Boston, Massachusetts, United States
Hms - Children'S Hosp. Boston, Div. of Infectious Diseases
Boston, Massachusetts, United States
Wne Maternal Pediatric Adolescent Aids Crs
Worcester, Massachusetts, United States
Rutgers - New Jersey Medical School Crs
Newark, New Jersey, United States
Suny Downstate Med. Ctr., Children'S Hosp. at Downstate Nichd Crs
Brooklyn, New York, United States
Harlem Hosp. Ctr. Ny Nichd Crs
New York, New York, United States
Metropolitan Hosp. Ctr.
New York, New York, United States
Nyu Ny Nichd Crs
New York, New York, United States
Strong Memorial Hospital Rochester Ny Nichd Crs
Rochester, New York, United States
Suny Stony Brook Nichd Crs
Stony Brook, New York, United States
Bronx-Lebanon Hosp. Impaact Crs
The Bronx, New York, United States
St. Christopher'S Hosp. for Children
Philadelphia, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Hepatitis B vaccineMeasles vaccine, livePneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein)PNEUMOCOCCAL POLYSACCHARIDE VACCINE

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Feb 2006
Primary completion: 31 Aug 2006
Completion: 31 Aug 2006
Last update posted: 1 Nov 2021
Registered enrollment: 101
Registry id: NCT00257127

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.