Clinical trialNCT00264758CompletedPhase 2/PHASE3Interventional

Frequent Hemodialysis Network: Daily Trial

SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Enrollment245End Stage Renal Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The Frequent Hemodialysis Network (FHN) Daily Trial is a randomized controlled trial recruiting subjects from dialysis units associated with designated Clinical Centers in the U.S. and Canada and followed for 1 year. Subjects will be randomized to either conventional hemodialysis Daily HD delivered for at least 2.5 hours (typically 3 to 4 hours), 3 days per week, or to more frequent hemodialysis delivered for 1.5 - 2.75 hours, 6 days per week. The study has two co-primary outcomes: 1) a composite of mortality with the change over 12 months in left ventricular mass by magnetic resonance imaging, and 2) a composite of mortality with the change over 12 months in the SF-36 RAND physical health composite (PHC) quality of life scale.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alan S. Kliger, M.D.
Yale New Haven Health System
Study Chair
clinicaltrials.gov ↗
Gerald J. Beck, Ph.D.
The Cleveland Clinic
Principal Investigator
clinicaltrials.gov ↗
Glenn Chertow, M.D.
University of California, San Francisco
Principal Investigator
clinicaltrials.gov ↗
Nathan W. Levin, M.D.
Renal Research Institute
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Paul W. Eggers, Ph.D.
NIDDK, NIH
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California at San Francisco - Core Center Plus Other Centers in California and Texas
San Francisco, California, United States
Renal Research Institute - Core Center Plus Other Centers in U.S. and Canada
New York, New York, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jan 2006
Primary completion: 31 Mar 2010
Completion: 31 Mar 2010
Last update posted: 3 Jul 2014
Registered enrollment: 245
Registry id: NCT00264758

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.