Clinical trialNCT00279318CompletedObservational

TEDDY - The Environmental Determinants of Diabetes in the Young

SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Enrollment8,667Type 1 Diabetes Mellitus

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The long-term goal of the TEDDY study is the identification of infectious agents, dietary factors, or other environmental agents, including psychosocial factors which trigger T1DM in genetically susceptible individuals or which protect against the disease. Identification of such factors will lead to a better understanding of disease pathogenesis and result in new strategies to prevent, delay or reverse T1DM.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Ake Lernmark, MD, PhD
Lund University
Principal Investigator
clinicaltrials.gov ↗
Anette G. Ziegler, MD
Diabetes Research Institute
Principal Investigator
clinicaltrials.gov ↗
Beena Akolkar, PhD
National Institutes of Diabetes and Digestive Kidney Diseases
Study Director
clinicaltrials.gov ↗
Jeffrey P. Krischer, PhD
University of South Florida
Principal Investigator
clinicaltrials.gov ↗
Jorma Toppari, MD, PhD
Wellbeing Services County of Southwest Finland
Principal Investigator
clinicaltrials.gov ↗
Marian J. Rewers, MD, PhD
University of Colorado Health Science Center
Principal Investigator
clinicaltrials.gov ↗
Richard McIndoe, PhD
Augusta University Research Institute, Inc.
Principal Investigator
clinicaltrials.gov ↗
William A. Hagopian, MD, PhD
Pacific Northwest Research Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Finland

Wellbeing Services County of Southwest Finland
Turku, Finland

Germany

Diabetes Research Institute
Munich, Germany

Sweden

Lund University
Malmö, Sweden

United States

University of Colorado Health Sciences Center
Denver, Colorado, United States
Augusta University
Gainesville, Florida, United States
Augusta University
Augusta, Georgia, United States
Pacific Northwest Research Institute
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Sept 2004
Primary completion: 30 Jun 2025
Completion: 30 Jun 2025
Last update posted: 22 Sept 2025
Registered enrollment: 8,667
Registry id: NCT00279318

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.