Clinical trialNCT00288054TerminatedPhase 1Interventional

S0429: Docetaxel, Cetuximab, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer

SponsorSWOG Cancer Research NetworkEnrollment24Lung Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some find tumor cells and kill them or carry tumor-killing substances to them. Others interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving docetaxel and cetuximab together with radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of docetaxel when given together with cetuximab and radiation therapy in treating patients with stage III non-small cell lung cancer.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Derick H. Lau, MD
University of California, Davis
Principal Investigator
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Karen Kelly, MD
University of Colorado, Denver
Principal Investigator
clinicaltrials.gov ↗
Kishan J. Pandya, MD
James P. Wilmot Cancer Center
Principal Investigator
clinicaltrials.gov ↗
Laurie E. Gaspar, MD, MBA
University of Colorado, Denver
Principal Investigator
clinicaltrials.gov ↗
Yuhchyau Chen, MD, PhD
James P. Wilmot Cancer Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

77 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Alaska Regional Hospital Cancer Center
Anchorage, Alaska, United States
Usc/norris Comprehensive Cancer Center and Hospital
Los Angeles, California, United States
Tibotec Therapeutics - Division of Ortho Biotech Products, Lp
Marysville, California, United States
University of California Davis Cancer Center
Sacramento, California, United States
University of Colorado Cancer Center at Uc Health Sciences Center
Aurora, Colorado, United States
Veterans Affairs Medical Center - Denver
Denver, Colorado, United States
Shaw Regional Cancer Center
Edwards, Colorado, United States
Poudre Valley Hospital
Fort Collins, Colorado, United States
Valley View Hospital Cancer Center
Glenwood Springs, Colorado, United States
Montrose Memorial Hospital Cancer Center
Montrose, Colorado, United States
Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus
Boca Raton, Florida, United States
Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - West
Boca Raton, Florida, United States
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
Savannah, Georgia, United States
Pearlman Comprehensive Cancer Center at South Georgia Medical Center
Valdosta, Georgia, United States
Cardinal Bernardin Cancer Center at Loyola University Medical Center
Maywood, Illinois, United States
Hematology Oncology Consultants - Naperville
Naperville, Illinois, United States
Hospital District Sixth of Harper County
Anthony, Kansas, United States
Cancer Center of Kansas, Pa - Chanute
Chanute, Kansas, United States
Cancer Center of Kansas, Pa - Dodge City
Dodge City, Kansas, United States
Cancer Center of Kansas, Pa - El Dorado
El Dorado, Kansas, United States
Cancer Center of Kansas - Fort Scott
Fort Scott, Kansas, United States
Cancer Center of Kansas-Independence
Independence, Kansas, United States
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
Kansas City, Kansas, United States
Cancer Center of Kansas, Pa - Kingman
Kingman, Kansas, United States
Lawrence Memorial Hospital
Lawrence, Kansas, United States
Southwest Medical Center
Liberal, Kansas, United States
Cancer Center of Kansas, Pa - Newton
Newton, Kansas, United States
Olathe Cancer Center
Olathe, Kansas, United States
Cancer Center of Kansas, Pa - Parsons
Parsons, Kansas, United States
Cancer Center of Kansas, Pa - Pratt
Pratt, Kansas, United States
Cancer Center of Kansas, Pa - Salina
Salina, Kansas, United States
Cotton-O'Neil Cancer Center
Topeka, Kansas, United States
Cancer Center of Kansas, Pa - Wellington
Wellington, Kansas, United States
Associates in Womens Health, Pa - North Review
Wichita, Kansas, United States
Ccop - Wichita
Wichita, Kansas, United States
Cancer Center of Kansas, Pa - Medical Arts Tower
Wichita, Kansas, United States
Cancer Center of Kansas, Pa - Wichita
Wichita, Kansas, United States
Via Christi Cancer Center at Via Christi Regional Medical Center
Wichita, Kansas, United States
Wesley Medical Center
Wichita, Kansas, United States
Cancer Center of Kansas, Pa - Winfield
Winfield, Kansas, United States

37 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cetuximab →Docetaxel →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Apr 2006
Primary completion: 30 Apr 2012
Completion: 30 Apr 2012
Last update posted: 4 Jan 2013
Registered enrollment: 24
Registry id: NCT00288054

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.