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Clinical trialNCT00297089CompletedPhase 1/PHASE2Interventional

A Phase 1/2 Study Evaluating ABT-751 in Combination With Alimta in Advanced Non-Small Cell Lung Cancer

SponsorAbbVie (prior sponsor, Abbott)Enrollment165Lung CancerNSCLCNon-Small-Cell Lung Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To determine the efficacy of ABT-751 when administered in combination with standard pemetrexed in subjects with advanced or metastatic NSCLC. The Phase 1 portion of the study is complete and the study is currently enrolling subjects in Phase 2.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

48 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Czechia
  • Site Reference Id/investigator# 3337

    Brno, Czechia

  • Site Reference Id/investigator# 4687

    Brno, Czechia

  • Site Reference Id/investigator# 4278

    Kyjov, Czechia

  • Site Reference Id/investigator# 3328

    Nový Jičín, Czechia

  • Site Reference Id/investigator# 3327

    Olomouc, Czechia

  • Site Reference Id/investigator# 3343

    Ostrava-Poruba, Czechia

  • Site Reference Id/investigator# 3342

    Prague, Czechia

  • Site Reference Id/investigator# 3344

    Prague, Czechia

  • Site Reference Id/investigator# 3411

    Příbram, Czechia

Greece
  • Site Reference Id/investigator# 3405

    Heraklion, Greece

  • Site Reference Id/investigator# 3403

    Thessaloniki, Greece

  • Site Reference Id/investigator# 3406

    Thessaloniki, Greece

Hungary
  • Site Reference Id/investigator# 3331

    Budapest, Hungary

  • Site Reference Id/investigator# 3333

    Miskolc, Hungary

  • Site Reference Id/investigator# 3332

    Székesfehérvár, Hungary

Netherlands
  • Site Reference Id/investigator# 3409

    Amsterdam, Netherlands

  • Site Reference Id/investigator# 3319

    Eindhoven, Netherlands

  • Site Reference Id/investigator# 3341

    Haraderwijk, Netherlands

  • Site Reference Id/investigator# 3528

    Hoorn, Netherlands

Slovakia
  • Site Reference Id/investigator# 3400

    Bratislava, Slovakia

  • Site Reference Id/investigator# 3410

    Martin, Slovakia

United States
  • Site Reference Id/investigator# 3358

    Fayetteville, Arkansas, United States

  • Site Reference Id/investigator# 4102

    Hot Springs, Arkansas, United States

  • Site Reference Id/investigator# 2127

    Greenbrae, California, United States

  • Site Reference Id/investigator# 2417

    Fort Collins, Colorado, United States

  • Site Reference Id/investigator# 5690

    Torrington, Connecticut, United States

  • Site Reference Id/investigator# 2411

    Fort Lauderdale, Florida, United States

  • Site Reference Id/investigator# 3363

    Lakeland, Florida, United States

  • Site Reference Id/investigator# 3352

    Port Saint Lucie, Florida, United States

  • Site Reference Id/investigator# 3807

    Atlanta, Georgia, United States

  • Site Reference Id/investigator# 3353

    Chicago, Illinois, United States

  • Site Reference Id/investigator# 3359

    Indianapolis, Indiana, United States

  • Site Reference Id/investigator# 2244

    Baltimore, Maryland, United States

  • Site Reference Id/investigator# 2416

    Baltimore, Maryland, United States

  • Site Reference Id/investigator# 2401

    Bethesda, Maryland, United States

  • Site Reference Id/investigator# 3793

    Peabody, Massachusetts, United States

  • Site Reference Id/investigator# 3362

    Worcester, Massachusetts, United States

  • Site Reference Id/investigator# 2075

    Kalamazoo, Michigan, United States

  • Site Reference Id/investigator# 2418

    Jefferson City, Missouri, United States

  • Site Reference Id/investigator# 4170

    St Louis, Missouri, United States

8 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ABT-751Pemetrexed →Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Nov 2006
Primary completion
31 Jan 2009
Completion
31 Jan 2009
Last update posted
31 Jan 2013
Registered enrollment
165
Registry id
NCT00297089

Cross-registrations

EU-CTR / CTIS (EudraCT)2006-002830-38
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.