Clinical trialNCT00301886WithdrawnPhase 3Interventional

S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone

SponsorSWOG Cancer Research NetworkEnrollment0Breast CancerHypercalcemia of MalignancyMetastatic CancerPain

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Zoledronate and ibandronate may prevent or help relieve bone pain and other symptoms caused by bone metastases. It is not yet known whether zoledronate is more effective than ibandronate in preventing bone problems caused by bone metastases due to breast cancer. PURPOSE: This randomized phase III trial is studying zoledronate to see how well it works compared to ibandronate in preventing bone problems in women with stage IV breast cancer that has spread to the bone.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Dawn Hershman, MD
Herbert Irving Comprehensive Cancer Center
Study ChairKOL profile →
clinicaltrials.gov ↗
Kathy S. Albain, MD
Loyola University
Study Chair
clinicaltrials.gov ↗
Saul E. Rivkin, MD
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Ibandronate →Zoledronate

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2006
Primary completion: 31 May 2006
Completion: 31 May 2006
Last update posted: 13 Nov 2013
Registered enrollment: 0
Registry id: NCT00301886

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.