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Clinical trialNCT00303953CompletedPhase 2Interventional

PXD101 in Treating Patients With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

SponsorNational Cancer Institute (NCI)Enrollment22Recurrent Adult Burkitt LymphomaRecurrent Adult Diffuse Large Cell Lymphoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial is studying how well PXD101 works in treating patients with relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma. PXD101 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

123 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Providence Hospital

    Mobile, Alabama, United States

  • University of Arizona Health Sciences Center

    Tucson, Arizona, United States

  • Nea Baptist Memorial Hospital

    Jonesboro, Arkansas, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, United States

  • East Bay Radiation Oncology Center

    Castro Valley, California, United States

  • Eden Hospital Medical Center

    Castro Valley, California, United States

  • Valley Medical Oncology Consultants-Castro Valley

    Castro Valley, California, United States

  • Valley Medical Oncology Consultants-Fremont

    Fremont, California, United States

  • Marin General Hospital

    Greenbrae, California, United States

  • Saint Rose Hospital

    Hayward, California, United States

  • Contra Costa Regional Medical Center

    Martinez, California, United States

  • Alta Bates Summit Medical Center - Summit Campus

    Oakland, California, United States

  • Bay Area Breast Surgeons Inc

    Oakland, California, United States

  • Bay Area Tumor Institute Ccop

    Oakland, California, United States

  • Highland General Hospital

    Oakland, California, United States

  • Larry G Strieff Md Medical Corporation

    Oakland, California, United States

  • Tom K Lee Inc

    Oakland, California, United States

  • Valley Care Health System - Pleasanton

    Pleasanton, California, United States

  • Valley Medical Oncology Consultants

    Pleasanton, California, United States

  • Doctors Medical Center- Jc Robinson Regional Cancer Center

    San Pablo, California, United States

  • Sutter Solano Medical Center

    Vallejo, California, United States

  • Cancer Centers of Central Florida Pa

    Leesburg, Florida, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, United States

  • Advocate Sherman Hospital

    Elgin, Illinois, United States

  • Loyola University Medical Center

    Maywood, Illinois, United States

  • Memorial Medical Center

    Springfield, Illinois, United States

  • Saint Francis Hospital and Health Centers

    Beech Grove, Indiana, United States

  • Reid Hospital and Health Care Services

    Richmond, Indiana, United States

  • Providence Medical Center

    Kansas City, Kansas, United States

  • Lawrence Memorial Hospital

    Lawrence, Kansas, United States

  • Menorah Medical Center

    Overland Park, Kansas, United States

  • Radiation Oncology Practice Corporation Southwest

    Overland Park, Kansas, United States

  • Salina Regional Health Center

    Salina, Kansas, United States

  • Shawnee Mission Medical Center

    Shawnee Mission, Kansas, United States

  • Baton Rouge General Medical Center

    Baton Rouge, Louisiana, United States

  • Mary Bird Perkins Cancer Center

    Baton Rouge, Louisiana, United States

  • Desoto Regional Health System

    Mansfield, Louisiana, United States

  • Louisiana State University Sciences Center- Monroe

    Monroe, Louisiana, United States

  • Interim Lsu Public Hospital

    New Orleans, Louisiana, United States

  • Louisiana State University Health Science Center

    New Orleans, Louisiana, United States

83 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Belinostat
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2006
Primary completion
31 Jan 2010
Completion
31 Aug 2010
Last update posted
12 May 2014
Registered enrollment
22
Registry id
NCT00303953

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.