Clinical trialNCT00305214CompletedInterventional

MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

SponsorMedtronic Cardiac Rhythm and Heart FailureEnrollment405Arrhythmia, VentricularIschemic CardiomyopathyMyocardial Infarction

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the study is to determine the usefulness of Microvolt T Wave Alternans (MTWA) testing of patients that have had a heart attack and have decreased pumping ability of the lower chamber of their heart. MTWA testing is a non-invasive test used to detect the likelihood of developing abnormally fast rhythms in the lower chambers of the heart. The objective of the study is to prove that if a patient has a positive MTWA test, they will be more likely to develop abnormally fast and dangerous rhythms in the lower chambers of the heart. The results of the study will help doctors to determine which patients would benefit the most from having an Implantable Cardioverter Defibrillator (ICD) implanted.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David G. Benditt, MD
University of Minnesota
Study Chair
clinicaltrials.gov ↗
Dean J. Kereiakes, MD, FACC
The Lindner Center for Research and Education
Study ChairKOL profile →
clinicaltrials.gov ↗
Theodore Chow, MD
The Lindner Center for Research and Education
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

47 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

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Mobile, Alabama, United States
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Phoenix, Arizona, United States
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Walnut Creek, California, United States
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Denver, Colorado, United States
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Hartford, Connecticut, United States
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Hollywood, Florida, United States
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Naples, Florida, United States
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Safety Harbor, Florida, United States
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Atlanta, Georgia, United States
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Joliet, Illinois, United States
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Springfield, Illinois, United States
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Beech Grove, Indiana, United States
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Kansas City, Kansas, United States
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New Orleans, Louisiana, United States
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Hyannis, Massachusetts, United States
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Grand Rapids, Michigan, United States
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Saginaw, Michigan, United States
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Saint Joseph, Michigan, United States
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Minneapolis, Minnesota, United States
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Omaha, Nebraska, United States
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Las Vegas, Nevada, United States
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East Islip, New York, United States
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Flushing, New York, United States
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West Islip, New York, United States
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Gastonia, North Carolina, United States
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Greensboro, North Carolina, United States
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High Point, North Carolina, United States
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Raleigh, North Carolina, United States
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Cincinnati, Ohio, United States
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Cleveland, Ohio, United States
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Columbus, Ohio, United States
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Toledo, Ohio, United States
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Doylestown, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Scranton, Pennsylvania, United States
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Spartanburg, South Carolina, United States
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Chattanooga, Tennessee, United States
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Germantown, Tennessee, United States
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Amarillo, Texas, United States

7 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2003
Primary completion: 28 Feb 2007
Completion: 28 Feb 2007
Last update posted: 13 Feb 2008
Registered enrollment: 405
Registry id: NCT00305214

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.