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Clinical trialNCT00318747TerminatedPhase 2Interventional

Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment140Allergic RhinitisAllergyAsthmaRhinitis, Allergic, Seasonal
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will test the effectiveness of an investigational treatment for patients with ragweed-induced asthma, sometimes called fall seasonal asthma. The treatment being tested is a series of anti-ragweed shots. The purpose of the study is to determine whether a short series of injections with Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate (AIC) can cause a long-lasting reduction in the symptoms of asthma that are caused by fall hay fever allergies.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Johns Hopkins University

    Baltimore, Maryland, United States

  • Bernstein Clinical Research Center, University of Cincinnati

    Cincinnati, Ohio, United States

  • Optimed Research, Ohio State University

    Columbus, Ohio, United States

  • Pennsylvania State University

    Hershey, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Apr 2006
Primary completion
—
Completion
30 Nov 2006
Last update posted
5 Feb 2013
Registered enrollment
140
Registry id
NCT00318747
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.