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Clinical trialNCT00321152CompletedPhase 4Interventional

A Study of 6(S)-5-MTHF Among Serotonin Reuptake Inhibitor(SSRI)-Resistant Outpatients With Major Depressive Disorder (MDD)

SponsorMassachusetts General HospitalEnrollment150Major Depressive Disorder
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California San Diego School of Medicine

    San Diego, California, United States

  • Rush University Medical Center, Psychiatric Medicine Associates, Llc

    Chicago, Illinois, United States

  • Lousiana State University Health Sciences Center

    New Orleans, Louisiana, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, United States

  • Burlington Medical Associates

    Burlington, Massachusetts, United States

  • Waltham Family Practice

    Waltham, Massachusetts, United States

  • Charles River Medical Associates

    Westborough, Massachusetts, United States

  • Univeristy of Cincinnati, College of Medicine

    Cincinnati, Ohio, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Southeast Health Consultants, Llc

    Charleston, South Carolina, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Nov 2006
Primary completion
31 Aug 2008
Completion
30 Jun 2010
Last update posted
8 Jun 2010
Registered enrollment
150
Registry id
NCT00321152

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.