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Clinical trialNCT00322270CompletedPhase 3Interventional

Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters

SponsorARCA Biopharma, Inc.Catheter OcclusionThrombosisVenous Thrombosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the safety profile of alfimeprase as assessed by monitoring of adverse events, serious adverse events and major bleeding events for up to 120 minutes following the instillation of study drug to an occluded central venous access device.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

18 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Desert Oasis Cancer Center

    Casa Grande, Arizona, United States

  • Cancer Research & Prevention Center

    Soquel, California, United States

  • Bethesda Research Center

    Boynton Beach, Florida, United States

  • Pasco Hernando Oncology Associates

    Brooksville, Florida, United States

  • Mercy Hospital

    Miami, Florida, United States

  • Pasco Hernando Oncology Associate

    New Port Richey, Florida, United States

  • Medical and Surgical Specialists

    Galesburg, Illinois, United States

  • Cancer Center at Blessing Hospital

    Quincy, Illinois, United States

  • Kalamazoo Hematology and Oncology

    Kalamazoo, Michigan, United States

  • Sparrow Cancer Center

    Lansing, Michigan, United States

  • Comprehensive Cancer Care Clinic

    Jefferson City, Missouri, United States

  • the Center for Cancer Care and Research

    St Louis, Missouri, United States

  • Umdnj-Robert Wood Johnson Medical School

    New Brunswick, New Jersey, United States

  • Dakota Cancer Institute

    Fargo, North Dakota, United States

  • Gabrail Cancer Center

    Canton, Ohio, United States

  • Hematology/oncology Consultants, Inc.

    Columbus, Ohio, United States

  • Texas Oncology, P.A.

    Dallas, Texas, United States

  • Carilion Gynecology/oncology

    Roanoke, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Alfimeprase
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2006
Primary completion
—
Completion
—
Last update posted
15 Aug 2008
Registered enrollment
—
Registry id
NCT00322270
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.