findmyKOL
Clinical trialNCT00326339CompletedPhase 2Interventional

Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)

SponsorRigel PharmaceuticalsEnrollment189Rheumatoid Arthritis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid). Approximately 180 patients who have had rheumatoid arthritis for a minimum of 12 months and who have been receiving a weekly methotrexate (MTX) dose for a minimum of 6 months will be enrolled into the study.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

38 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Mexico
  • Hospital Aranda de la Parra

    León, GT, Mexico

  • Hospital Civil de Guadalajara "dr. Juan I. Menchaca"

    Guadalajara, JA, Mexico

  • Hospital Civil de Guadalajara "fray Antonio Alcalde"

    Guadalajara, JA, Mexico

  • Centro Médico del Instituto de Seguridad Social del Estado de Mexico Y Municipios (cmissemym)

    Metepec, MX, Mexico

  • Arke Estudios Clinicos, S.A. de C.V.

    Mexico City, Mexico City, Mexico

  • Centro Médico Dalinde

    Mexico City, Mexico City, Mexico

  • Clinica Para El Diagnostico Y Tratamiento de Las Enfermedades Reumaticas, S.C.

    Mexico City, Mexico City, Mexico

  • Hospital General de Mexico

    Mexico City, Mexico City, Mexico

  • Hospital Regional "1° de Octubre", Issste

    Mexico City, Mexico City, Mexico

  • Facultad de Medicina Y Hospital Universitario "dr. Jose E. Gonzalez" de la Universidad Autonoma de Nuevo Leon

    Monterrey, Nuevo León, Mexico

  • Hospital Central "dr. Ignacio Morones Prieto"

    San Luis Potosí City, SL, Mexico

United States
  • Pacific Arthritis Center Medical Group

    Santa Maria, California, United States

  • Dmi Research

    Ocala, Florida, United States

  • Renstar Medical Research

    Ocala, Florida, United States

  • Arthritis & Osteoporosis Treatment Center

    Orange Park, Florida, United States

  • Arthritis Associates Inc.

    Orlando, Florida, United States

  • Arthritis Research of Florida

    Palm Harbor, Florida, United States

  • Arthritis Research of Florida, Inc.

    Palm Harbor, Florida, United States

  • Lovelace Scientific Resources

    Sarasota, Florida, United States

  • the Center for Arthritis and Rheumatic Diseas

    South Miami, Florida, United States

  • Coeur D'Alene Arthritis Clinical Trials

    Coeur d'Alene, Idaho, United States

  • the Arthritis Center

    Springfield, Illinois, United States

  • Mmg Clinical Research

    South Bend, Indiana, United States

  • Phase Iii Clinical Research

    Fall River, Massachusetts, United States

  • Michigan Arthritis Research Center

    Brighton, Michigan, United States

  • Westroad Medical Group

    Omaha, Nebraska, United States

  • Nc Arthritis & Allergy Care Center

    Raleigh, North Carolina, United States

  • Clinical Research Division

    Mayfield Village, Ohio, United States

  • Lynn Health Science Institute

    Oklahoma City, Oklahoma, United States

  • East Penn Rheumatology Associates

    Bethlehem, Pennsylvania, United States

  • Altoona Ctr. for Clinical Research

    Duncansville, Pennsylvania, United States

  • Clinical Research Center of Reading Llp

    West Reading, Pennsylvania, United States

  • Low Country Rheumatology

    Charleston, South Carolina, United States

  • Arthritis Clinic

    Jackson, Tennessee, United States

  • Scri

    Memphis, Tennessee, United States

  • Austin Rheumatology Research

    Austin, Texas, United States

  • Research Across America

    El Paso, Texas, United States

  • Center for Arth. & Rheum. Disease, Pc

    Chesapeake, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboR788
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2006
Primary completion
31 Oct 2007
Completion
31 Dec 2007
Last update posted
20 Apr 2009
Registered enrollment
189
Registry id
NCT00326339
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.