Clinical trialNCT00334815Active, not recruitingPhase 2Interventional

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

SponsorNational Cancer Institute (NCI)Enrollment29Lung AdenocarcinomaLung Adenosquamous CarcinomaLung Large Cell CarcinomaLung Squamous Cell CarcinomaMinimally Invasive Lung AdenocarcinomaStage IIIA Lung Non-Small Cell Cancer AJCC v7+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This clinical trial studies combination chemotherapy, radiation therapy, and bevacizumab in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as cisplatin, etoposide, and docetaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy) together with radiation therapy and bevacizumab may kill more tumor cells.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Antoinette J Wozniak
SWOG Cancer Research Network
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

61 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Providence Hospital
Mobile, Alabama, United States
Saint Bernards Regional Medical Center
Jonesboro, Arkansas, United States
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Highlands Oncology Group - Rogers
Rogers, Arkansas, United States
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Fremont - Rideout Cancer Center
Marysville, California, United States
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Providence Santa Rosa Memorial Hospital
Santa Rosa, California, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California, United States
Northbay Cancer Center
Vacaville, California, United States
Rocky Mountain Regional Va Medical Center
Aurora, Colorado, United States
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Denver Health Medical Center
Denver, Colorado, United States
Shaw Cancer Center
Edwards, Colorado, United States
Valley View Hospital Cancer Center
Glenwood Springs, Colorado, United States
Montrose Memorial Hospital
Montrose, Colorado, United States
Cancer Centers of Central Florida Pa
Leesburg, Florida, United States
Lewis Cancer and Research Pavilion at Saint Joseph'S/candler
Savannah, Georgia, United States
Loyola University Medical Center
Maywood, Illinois, United States
Edward Hospital/cancer Center
Naperville, Illinois, United States
Haysmed
Hays, Kansas, United States
Hutchinson Regional Medical Center
Hutchinson, Kansas, United States
University of Kansas Cancer Center
Kansas City, Kansas, United States
Olathe Cancer Center
Olathe, Kansas, United States
Salina Regional Health Center
Salina, Kansas, United States
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, United States
Highland Clinic
Shreveport, Louisiana, United States
Lsu Health Sciences Center at Shreveport
Shreveport, Louisiana, United States
Dana-Farber Cancer Institute at Boston Medical Center - Brighton
Brighton, Massachusetts, United States
Wayne State University/karmanos Cancer Institute
Detroit, Michigan, United States
Mclaren Cancer Institute-Macomb
Mount Clemens, Michigan, United States
University of Mississippi Medical Center
Jackson, Mississippi, United States
Kansas City Veterans Affairs Medical Center
Kansas City, Missouri, United States
Montana Cancer Consortium Ncorp
Billings, Montana, United States
Benefis Sletten Cancer Institute
Great Falls, Montana, United States
Arnot Ogden Medical Center/falck Cancer Center
Elmira, New York, United States
Highland Hospital
Rochester, New York, United States
University of Rochester
Rochester, New York, United States
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States

21 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bevacizumab →Cisplatin →Docetaxel →Etoposide →Filgrastim →Pegfilgrastim →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Jun 2006
Primary completion: 1 Jul 2014
Completion: 22 Feb 2027
Last update posted: 29 Jul 2026
Registered enrollment: 29
Registry id: NCT00334815

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.